Project description
A new approach for controlling virus infection
Viral outbreaks necessitate a front line of antiviral strategies since the on-demand development of vaccines or antibody treatment is not always feasible. The EU-funded LOFlu project will investigate the host-pathogen interactions in influenza A virus (IAV) infection. Particular emphasis will be given to viral inclusions with liquid properties that form during viral assembly and constitute a key step in the virus life cycle. By studying how the host and the virus work in concert to coordinate the formation and material properties of IAV liquid inclusions and their interactions, researchers will shed light on the organisation of viral reactions in space and in time, as well as on the principles governing the assembly of IAV epidemic and pandemic genomes.
Fields of science
- natural sciencesbiological sciencesmicrobiologyvirology
- medical and health scienceshealth sciencesinfectious diseasesRNA virusesebola
- medical and health scienceshealth sciencespublic healthepidemiologypandemics
- medical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenza
- natural sciencesbiological sciencesgeneticsgenomes
Programme(s)
Funding Scheme
ERC-COG - Consolidator GrantHost institution
1067-001 Lisboa
Portugal
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Beneficiaries (1)
1067-001 Lisboa
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