Project description DEENESFRITPL Insight into mercury toxicity from fish Mercury is one of the top ten chemicals of major public health concern as identified by the WHO. With fish and seafood being the principal human exposure sources to mercury, the effects of mercury on humans warrant further investigation. The EU-funded MERFISH project will employ novel analytical approaches to study the impact of mercury on proteins and estimate the detoxification role of selenium, offering insight into human health risks and benefits. Results will help formulate important guidelines for vulnerable populations such as pregnant women and young children on avoiding certain fish species with high mercury content. Show the project objective Hide the project objective Objective MERFISH brings together international experts from a wide array of interdisciplinary research areas (analytical chemistry, fish nutrition, environmental science, communication, toxicology & aquaculture) from industry and academia from EU, Brazil and Mauritius, with a long-term goal of furthering the understanding of the source, transport, fate and effects of mercury from fish to humans and the detoxification role of selenium. MERFISH surges from a global demand, directly related to mercury, one of the top ten chemicals of major public health concern identified by the World Health Organization. However, mercury metabolic pathways in biota still remain poorly understood. Its understanding is crucial to elucidate its (eco)toxic effect and to identify important drivers of the mercury biogeochemical cycle.Fish and seafood consumption is the principal human exposure source to (toxic) methymercury. EU food safety authorities (such as EFSA), and well-known US and United Nation environmental and food organizations (such as USEPA and FAO) clearly advise about avoiding certain fish species for vulnerable populations (including pregnant women and young children) depending on their methymercury concentrations. Mercury binding with proteins has been identified as a potential cause for toxicity and the role of selenium as antagonist for mercury toxicity has been identified but not well understood. MERFISH is based on the development of novel analytical approaches to gather new knowledge about mercury and selenium mechanisms in fish and humans. The project will be a critical contribution to establishing more realistic scenarios to estimate human health risk and benefits, but also to better capture the economic impacts on commercial fisheries. MERSFISH will build a lasting research network to answer emerging challenges in analytical chemistry, food safety, trophic transfer, fish nutrition and environmental and human health related to the global mercury issue. Fields of science natural scienceschemical sciencesanalytical chemistrynatural scienceschemical sciencesinorganic chemistrytransition metalsnatural sciencesearth and related environmental sciencesenvironmental sciencesengineering and technologyother engineering and technologiesfood technologyfood safetynatural sciencesbiological scienceszoologyichthyology Keywords Mercury selenium stable isotopes speciation Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Topic(s) MSCA-RISE-2020 - Research and Innovation Staff Exchange Call for proposal H2020-MSCA-RISE-2020 See other projects for this call Funding Scheme MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinator CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Net EU contribution € 78 200,00 Address RUE MICHEL ANGE 3 75794 Paris France See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 174 800,00 Participants (7) Sort alphabetically Sort by Net EU contribution Expand all Collapse all INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT France Net EU contribution € 9 200,00 Address 147 RUE DE L'UNIVERSITE 75007 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 9 200,00 HAVFORSKNINGSINSTITUTTET Norway Net EU contribution € 46 000,00 Address NORDNESGATEN 50 5817 Bergen See on map Region Norge Vestlandet Vestland Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 50 600,00 INSTITUT JOZEF STEFAN Slovenia Net EU contribution € 69 000,00 Address Jamova 39 1000 Ljubljana See on map Region Slovenija Zahodna Slovenija Osrednjeslovenska Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 73 600,00 ADVANCED ISOTOPIC ANALYSIS France Net EU contribution € 13 800,00 Address 2 AVENUE DU PRESIDENT PIERRE ANGOT TECHNOPOLE HELI 64000 Pau See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nouvelle-Aquitaine Aquitaine Pyrénées-Atlantiques Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 13 800,00 PS ANALYTICAL LIMITED United Kingdom Net EU contribution € 0,00 Address ARTHUR HOUSE CRAYFIELDS INDUSTRIAL BR5 3HP Orpington See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region London Outer London — South Bromley Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data EUROPE FOR BUSINESS LTD United Kingdom Net EU contribution € 59 800,00 Address 520, BIRCHWOOD BOULEVARD BIRCHWOOD WA3 7QX Warrington See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region North West (England) Cheshire Warrington Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 59 800,00 UNIVERSIDAD COMPLUTENSE DE MADRID Spain Net EU contribution € 13 800,00 Address AVENIDA DE SENECA 2 28040 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 13 800,00 Partners (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. MARINE BIOTECHNOLOGY PRODUCTS LTD Mauritius Net EU contribution € 0,00 Address MOTORWAY M2, RICHE TERRE Port Louis See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 4 600,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSIDADE DE SAO PAULO Brazil Net EU contribution € 0,00 Address RUA DA REITORIA 109 BUTANTA 05508 900 Sao Paulo Sp See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 105 800,00
