Proton versus Photon Therapy for Esophageal Cancer - a Trimodality Strategy

Project Information

PROTECT-trial

Grant agreement ID: 101008134

DOI

10.3030/101008134

EC signature date 7 July 2021

Start date 1 July 2021

End date 30 June 2027

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

€ 4 763 733,75

EU contribution

€ 1 500 000,00

Coordinated by

AARHUS UNIVERSITET
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (14)

A study protocol for a non-blinded multi-center RCT

A study protocol for a nonblinded multicenter RCT

Dissemination and Exploitation Plan
Patient information materials
First general Assembly

Minutes of General Assembly M18

Annual meeting with EPTN and other networks, societies, and industry M41

Report from annual meeting with EPTN and other networks, societies, and industry M41

Annual meeting with EPTN and other networks, societies, and industry M17

Report from annual meeting with EPTN and other networks societies and industry M17

Second general Assembly

Minutes of General Assembly

Protocol for radiation therapy QA
Annual meeting with EPTN and other networks, societies, and industry M53

Report from annual meeting with EPTN and other networks, societies, and industry M53

Annual meeting with EPTN and other networks, societies, and industry M5

Report from annual meeting with EPTN and other networks societies and industry M5

Registration of study in an approved registry
Annual meeting with EPTN and other networks, societies, and industry M29

Report from annual meeting with EPTN and other networks, societies, and industry M29

Protocol for surgery QA
Project handbook, including timeline for meetings, reporting and related activities

Project handbook including timeline for meetings reporting and related activities

Websites, patent fillings, videos etc. (2)

During trial patient information materials
External project webpage

Open Research Data Pilot (1)

Data and IPR Management Plan

Demonstrators, pilots, prototypes (1)

Dissemination toolkit

Publications

Peer reviewed articles (5)

Treatment planning comparison in the PROTECT-trial randomising proton versus photon beam therapy in oesophageal cancer: Results from eight European centres

Author(s): Lone Hoffmann, Hanna Mortensen, Muhammad Shamshad, Maaike Berbee, Nicola Bizzocchi, Rebecca Bütof, Richard Canters, Gilles Defraene, Mai Lykkegaard Ehmsen, Francesca Fiorini, Karin Haustermans, Ryan Hulley, Erik W. Korevaar, Matthew Clarke, Sebastian Makocki, Christina T. Muijs, Luke Murray, Owen Nicholas, Marianne Nordsmark, Ganesh Radhakrishna, Ditte Sloth Møller.
Published in: Radiotherapy and Oncology, Issue Volume 172, 2022, Page(s) Pages 32-41, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2022.04.029

Towards a European prospective data registry for particle therapy

Author(s): Cai Grau, Alexandru Dasu, Esther G.C. Troost, Karin Haustermans, Damien C. Weber, Johannes A. Langendijk, Vincent Gregoire, Ester Orlandi, Juliette Thariat, Neige Journy, Abdulhamid Chaikh, Aurelie Isambert, Barbara Alicja Jereczek-Fossa, Ana Vaniqui, Pavel Vitek, Renata Kopec, Rianne Fijten, Carola Luetgendorf-Caucig, Pawel Olko
Published in: Radiotherapy and Oncology, Issue 196, 2024, Page(s) 110293, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2024.110293

Proton versus photon therapy for esophageal cancer – A trimodality strategy (PROTECT) NCT050555648

Author(s): H.R. Mortensen, P. Populaire, L. Hoffmann, D.S. Moeller, A. Appelt, P. Nafteux, C.T. Muijs, C. Grau, M.A. Hawkins, E.G.C. Troost, G. Defraene, R. Canters, C.S. Clarke, D.C. Weber, E.W. Korevaar, K. Haustermans, M. Nordsmark, Val Gebski, M.P. Achiam, Sheraz R. Markar, Ganesh Radhakrishna, Maaike Berbee, Daniele Scartoni, Ester Orlandi, Jerome Doyen, Vincent Gregoire, Gilles Crehange, Johannes Lange
Published in: Radiotherapy and Oncology, Issue 190, 2024, Page(s) 109980, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2023.109980

Bone versus soft-tissue setup in proton therapy for patients with oesophageal cancer

Author(s): Muhammad Shamshad, Ditte Sloth Møller, Hanna Rahbek Mortensen, Mai Lykkegaard Ehmsen, Maria Fuglsang Jensen, Lone Hoffmann.
Published in: Acta Oncologica, Issue Volume 61, 2022 - Issue 8, 2022, Page(s) Pages 994-1003, ISSN 0284-186X
Publisher: Taylor & Francis
DOI: 10.1080/0284186x.2022.2091949

Radiotherapy quality assurance in the PROTECT trial – a European randomised phase III-trial comparing proton and photon therapy in the treatment of patients with oesophageal cancer

Author(s): Camilla Skinnerup Byskov, Hanna R. Mortensen, Marie-Claude Biston, Sara Broggi, Rebecca Bütof, Richard Canters, Gilles Crehange, Gilles Defraene, Jerome Doyen, Mai L. Ehmsen, Silvia Fabiano, Francesco Fracchiola, Farid Goudjil, Karin Haustermans, Sarah E. Jensen, Maria F. Jensen, Marie Lecornu, Sebastian Makocki, Aurélia L. Mana, Andrea Martignano, Arturs Meijers, Alfredo Mirandola, Diana A. Mit
Published in: Acta Oncologica, Issue 64, 2025, Page(s) 406-414, ISSN 1651-226X
Publisher: MJS Publishing, Medical Journals Sweden AB
DOI: 10.2340/1651-226x.2025.42774