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Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic: ORCHESTRA

Objective

The ORCHESTRA project provides an innovative approach to learn from the SARS-CoV-2 health crisis and derive recommendations for increasing preparedness for future outbreaks. The main outcome of the project is the creation of a new pan-European cohort built on existing and new large-scale population cohorts in European and non-European countries. Data analysis through a federated learning technique supported by advanced modelling capabilities will allow the integration of epidemiological, clinical, microbiological and genotypic aspects of population-based cohorts with environment and socio-economic features. The ORCHESTRA cohort will include SARS-CoV-2 infected and non-infected individuals of all ages and conditions and thereby enabling a retrospective evaluation of risk factors for the disease acquisition and progression of the disease and prospective follow-up aimed at exploring long-term consequences and analysis of vaccination response when vaccines will be available. To better address these research questions, the ORCHESTRA-cohort will include adequately sampled representatives of general populations, COVID-19 patients and special ‘at risk’ populations of fragile individuals and health-care workers. The project will assess also health costs of COVID-19 with special emphasis on delayed health services in the fragile populations. The participation of non-European and Low-Medium Income Countries and a Global COVID-19 Guidance group of major stakeholders and investigators from successful clinical trials addressing therapeutic approaches to COVID-19, ensures inclusion of all expertise needed and translation of recommendations to different social and economic settings. The project will significantly impact on the responsiveness to SARS-CoV-2 and can be used as a model for responsiveness for new public health threats.

Call for proposal

H2020-SC1-PHE-CORONAVIRUS-2020-2-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITA DEGLI STUDI DI VERONA
Address
Via Dell Artigliere 8
37129 Verona
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 273 123,75

Participants (25)

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 2 324 857,50
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 2 431 201
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
SERVICIO ANDALUZ DE SALUD
Spain
EU contribution
€ 567 596,25
Address
Avenida De La Constitucion 18
41071 Sevilla
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
CINECA CONSORZIO INTERUNIVERSITARIO
Italy
EU contribution
€ 787 312,50
Address
Via Magnanelli 6/3
40033 Casalecchio Di Reno Bo
Activity type
Research Organisations
LUXEMBOURG INSTITUTE OF HEALTH
Luxembourg
EU contribution
€ 894 601,25
Address
Val Fleuri 84
1526 Luxembourg
Activity type
Research Organisations
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 382 500
Address
3 Avenue Victoria
75000 Paris
Activity type
Research Organisations
REGIONE EMILIA ROMAGNA
Italy
EU contribution
€ 826 356,38
Address
Via Aldo Moro 52
40127 Bologna
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
EU contribution
€ 286 328,25
Address
C Rossello 132 Planta 05
08036 Barcelona
Activity type
Research Organisations
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 1 388 179,41
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT ANTWERPEN
Belgium
EU contribution
€ 1 098 210,75
Address
Prinsstraat 13
2000 Antwerpen
Activity type
Higher or Secondary Education Establishments
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany
EU contribution
€ 1 234 959,38
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Activity type
Research Organisations
KLINIKUM DER UNIVERSITAET ZU KOELN
Germany
EU contribution
€ 1 184 381,25
Address
Kerpener Strasse 62
50937 Koeln
Activity type
Higher or Secondary Education Establishments
FONDAZIONE PENTA - FOR THE TREATMENT AND CARE OF CHILDREN WITH HIV ANDRELATED DISEASES - ONLUS
Italy
EU contribution
€ 146 249,50
Address
Corso Stati Uniti 4
35127 Padova
Activity type
Research Organisations
UNIVERSITY OF STUTTGART
Germany
EU contribution
€ 684 937,50
Address
Keplerstrasse 7
70174 Stuttgart
Activity type
Higher or Secondary Education Establishments
Centre de Recherches Medicales de Lambaréné
Gabon
EU contribution
€ 360 000
Address
Na
118 Lambaréné
Activity type
Research Organisations
REGIONALNY URAD VEREJNEHO ZDRAVOTNICTVA SO SIDLOM V BANSKEJ BYSTRICI
Slovakia
EU contribution
€ 87 750
Address
Cesta K Nemocnici 622 1
975 56 Banska Bystrica
Activity type
Research Organisations
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 659 100
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
EU contribution
€ 443 625
Address
Hanzeplein 1
9713 GZ Groningen
Activity type
Higher or Secondary Education Establishments
CENTRE INFORMATIQUE NATIONAL DE L'ENSEIGNEMENT SUPERIEUR
France
EU contribution
€ 711 750
Address
950 Rue De St Priest
34097 Montpellier
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
UNIVERSIDAD DE OVIEDO
Spain
EU contribution
€ 146 250
Address
Calle San Francisco 3
33003 Oviedo
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD DE BUENOS AIRES
Argentina
EU contribution
€ 80 000
Address
Calle Viamonte 430
1053 Buenos Aires
Activity type
Higher or Secondary Education Establishments
INSTITUTUL NATIONAL DE SANATATE PUBLICA
Romania
EU contribution
€ 173 013,75
Address
Str Dr Leonte 1-3 Sector 5
050463 Bucuresti
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
EU contribution
€ 235 609
Address
Im Neuenheimer Feld 672
69120 Heidelberg
Activity type
Higher or Secondary Education Establishments
REGIONE DEL VENETO
Italy
EU contribution
€ 246 000
Address
Palazzo Balbi - Dorsoduro 3901
30123 Venezia
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
FONDATION CONGOLAISE POUR LA RECHERCHE MEDICALE
Congo
EU contribution
€ 233 750
Address
Villa D6 Campus Who/afro Djoue
Brazzaville
Activity type
Other