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Bridging the Early Diagnosis and Treatment Gap of Brain Diseases via Smart, Connected, Proactive and Evidence-based Technological Interventions

Periodic Reporting for period 2 - ALAMEDA (Bridging the Early Diagnosis and Treatment Gap of Brain Diseases via Smart, Connected, Proactive and Evidence-based Technological Interventions)

Reporting period: 2022-07-01 to 2023-12-31

In the realm of brain disease research, technological strides have proven remarkably potent. The combination of Big Data Analytics, wearable sensors and Machine Learning techniques provide a wealth of clinically actionable insights, seamlessly complementing medical advice and enriching treatment protocols. The significance of this achievement is underscored by the escalating burden of neurological disorders, ranking third in terms of disability-adjusted life-years (DALYs), trailing only cancer and cardiovascular diseases. ALAMEDA stands as a monitoring, assessment and understanding framework within the complex landscape of brain disorders, more specifically Multiple Sclerosis, Parkinsons Disease and Stroke, acknowledging the evolving complexities that can erode quality of life for patients and caregivers alike. Consistent evaluations serve as crucial elements, guaranteeing the effectiveness of interventions and anticipating potential relapse occurrences. At its core, ALAMEDA is a pioneer endeavor, dedicated to resolving the current bottleneck and necessity of timely brain disease progression through the fusion of Artificial Intelligence, wearable non-intrusive sensors, software applications, clinical expertise, and user experience metrics. Three years of relentless dedication have been invested in fortifying outcome predictability and refining disease management strategies. Through the harmonization of cutting-edge AI, mHealth apps, and sensor technologies, a symbiotic ecosystem has emerged, co-crafted with input from both patients and clinicians.

One of the most distinguishing achievements of this collaborative effort is the ALAMEDA Data Collection Journey. Embracing the moral of proactive and continuous healthcare, this journey employs unobtrusive health monitoring through wearable devices and smartphone applications. Motor functions, sleep patterns, emotional well-being, and quality of life are carefully, continuously monitored and analyzed, empowering healthcare professionals with otherwise hidden insights, while preserving patient comfort and privacy. Furthermore, ALAMEDA exhibited a new era of technological breakthroughs with its AI and Digital Tools for brain diseases assessment. Innovative AI/ML models and tools have been carefully crafted while their predictive robustness has been explored through rigorous analysis and parallel assessment by clinical experts. The integration of wearable and IoT sensors, including the unobtrusive sleep monitoring and belt sensors developed within ALAMEDA, exemplifies the consortium's unwavering commitment to revolutionizing patient care. ALAMEDA’s legacy lies not only in the advancements achieved but also, and maybe more important, in the promise it holds for reshaping the future of brain disease management.
In the realm of brain disease research, technological strides have proven remarkably potent. The combination of Big Data analytics, wearable sensors and Machine Learning provide a wealth of clinically actionable insights, seamlessly complementing medical advice and enriching treatment protocols. The significance is underscored by the escalating burden of neurological disorders, ranking third in terms of disability-adjusted life-years (DALYs), trailing only cancer and cardiovascular diseases. ALAMEDA stands as a monitoring, assessment and understanding framework within the complex landscape of brain disorders, more specifically Multiple Sclerosis, Parkinsons Disease and Stroke, acknowledging the evolving complexities that can erode quality of life for patients and caregivers alike. Consistent evaluations serve as crucial elements, guaranteeing the effectiveness of interventions and anticipating potential relapse occurrences. At its core, ALAMEDA is a pioneer endeavor, dedicated to resolving the current bottleneck and necessity of timely brain disease progression through the fusion of Artificial Intelligence, wearable non-intrusive sensors, software applications, clinical expertise, and user experience metrics. Three years of relentless dedication have been invested in fortifying outcome predictability and refining disease management strategies. Through the harmonization of cutting-edge AI, mHealth apps, and sensor technologies, a symbiotic ecosystem has emerged, co-crafted with input from both patients and clinicians.
A distinguishing achievement of the project is the ALAMEDA Data Collection Journey. Embracing the moral of proactive and continuous healthcare, this journey employs unobtrusive health monitoring through wearable devices and smartphone applications. Motor functions, sleep patterns, emotional well-being, and quality of life are carefully, continuously monitored and analyzed, empowering healthcare professionals with otherwise hidden insights, while preserving patient comfort and privacy. Furthermore, ALAMEDA exhibited a new era of technological breakthroughs with its AI and Digital Tools for brain diseases assessment. Innovative AI/ML models and tools have been carefully crafted while their predictive robustness has been explored through rigorous analysis and parallel assessment by clinical experts. The integration of wearable and IoT sensors, including the unobtrusive sleep monitoring and belt sensors developed within ALAMEDA, exemplifies the consortium's unwavering commitment to revolutionizing patient care. ALAMEDA’s legacy lies not only in the advancements achieved but also, and maybe more important, in the promise it holds for reshaping the future of brain disease management.
ALAMEDA's approach to tackling the challenge of evaluating and assessing the disease status of patients with either Multiple Sclerosis, Parkinsons Disease or Stroke (in general not limited, but can also be used in the future for other chronic brain diseases) is innovative and comprehensive. By bringing together the right technical and medical experts within a consortium, the project targeted in revolutionizing patients’ monitoring and disease progression with the overarching goal of enhancing patients' quality of life,,while also medical experts are constantly aware of their status with enriched and unbiased insights.
ALAMEDA's approach to tackle the challenge of evaluating and assessing the disease status of patients with either Multiple Sclerosis, Parkinsons Disease or Stroke is innovative and comprehensive. By bringing together the right technical and medical experts within a consortium, the project targeted in revolutionizing patients’ monitoring and disease progression with the overarching goal of enhancing patients' quality of life, while also medical experts are constantly aware of their status with enriched and unbiased insights. One key aspect of ALAMEDA's strategy is the utilization of digital technologies to gather rich diagnostic/evaluation data streams, capitalizing the expertise of clinical professionals to ensure the data collected is relevant and informative while being minimally intrusive in patients’ daily lives. The integration of the patient’s input on acceptability and usability in their daily lives, ALAMEDA ensures a holistic monitoring approach. ALAMEDA employs Big Data and AI methods to analyze the collected data streams, targeting disease progression assessment and provides personalized healthcare guidance. Outcome insights complement existing medical protocols and enable clinical practitioners to remotely monitor their patient in an unbiased and continuous way.
Parkinson Data Collection Journey
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ALAMEDA Technological Ecosystem
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ALAMEDA AI-Toolkit
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