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Cardiac open reading frame edition to study cardiomyopathies in pigs

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Thymosin ß4 and MRTF-A mitigate vessel regression despite cardiovascular risk factors (opens in new window)

Author(s): Kupatt C, Ziegler T, Bähr A, Le Noble F
Published in: International immunopharmacology, Issue 117, 2023, Page(s) 109786, ISSN 1878-1705
Publisher: Elsevier Science
DOI: 10.1016/j.intimp.2023.109786

Endothelial Retargeting of AAV9 In Vivo (opens in new window)

Author(s): Bozoglu T, Lee S, Ziegler T, Jurisch V, Maas S, Baehr A, Hinkel R, Hoenig A, Hariharan A, Kim CI, Decker S, Sami H, Koppara T, Oellinger R, Müller OJ, Frank D, Megens R, Nelson P, Weber C, Schnieke A, Sperandio M, Santamaria G, Rad R, Moretti A, Laugwitz KL, Soehnlein O, Ogris M, Kupatt C
Published in: Advanced Science, Issue 9, 2022, Page(s) e2103867, ISSN 2198-3844
Publisher: WILEY-VCH
DOI: 10.1002/advs.202103867

Cellular pathophysiology of Duchenne muscular dystrophy: insights from a novel rhesus macaque model (opens in new window)

Author(s): Alessandra Moretti, Christian Kupatt, Eckhard Wolf
Published in: Signal Transduction and Targeted Therapy, Issue 9, 2024, Page(s) 357, ISSN 2059-3635
Publisher: Nature Publishing Group
DOI: 10.1038/s41392-024-02061-2

Recapitulating porcine cardiac development in vitro: from expanded potential stem cell to embryo culture models (opens in new window)

Author(s): Rawat H, Kornherr J, Zawada D, Bakhshiyeva S, Kupatt C, Laugwitz KL, Bähr A, Dorn T, Moretti A, Nowak-Imialek M
Published in: Frontiers in cell and developmental biology, Issue 11, 2023, Page(s) 1111684, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2023.1111684

Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors (opens in new window)

Author(s): Poch CM, Foo KS, De Angelis MT, Jennbacken K, Santamaria G, Bähr A, Wang QD, Reiter F, Hornaschewitz N, Zawada D, Bozoglu T, My I, Meier A, Dorn T, Hege S, Lehtinen ML, Tsoi YL, Hovdal D, Hyllner J, Schwarz S, Sudhop S, Jurisch V, Sini M, Fellows MD, Cummings M, Clarke J, Baptista R, Eroglu E, Wolf E, Klymiuk N, Lu K, Tomasi R, Dendorfer A, Gaspari M, Parrotta E, Cuda G, Krane M, Sinnecker D, Hop
Published in: Nature Cell Biology, Issue 24, 2022, Page(s) 659-671, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-022-00899-8

Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52 (opens in new window)

Author(s): Stirm M, Shashikadze B, Blutke A, Kemter E, Lange A, Stöckl JB, Jaudas F, Laane L, Kurome M, Keßler B, Zakhartchenko V, Bähr A, Klymiuk N, Nagashima H, Walter MC, Wurst W, Kupatt C, Fröhlich T, Wolf E
Published in: Proceedings of the National Academy of Sciences of the United States of America, Issue 120, 2023, Page(s) e2301250120, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2301250120

Parenchymal cues define Vegfa-driven venous angiogenesis by activating a sprouting competent venous endothelial subtype (opens in new window)

Author(s): Préau L, Lischke A, Merkel M, Oegel N, Weissenbruch M, Michael A, Park H, Gradl D, Kupatt C, le Noble F
Published in: Nature communications, Issue 15, 2024, Page(s) 3118, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-47434-x

Pig models for translational Duchenne muscular dystrophy research (opens in new window)

Author(s): Stirm M, Klymiuk N, Nagashima H, Kupatt C, Wolf E
Published in: Trends in molecular medicine, Issue 2024 May 14, 2024, Page(s) S1471-4914(24)00101-1, ISSN 1471-4914
Publisher: Elsevier BV
DOI: 10.1016/j.molmed.2024.04.013

Intellectual Property Rights

AAV VECTORS FOR GENE THERAPY IN ENDOTHELIAL CELLS

Application/Publication number: 20 22086634
Date: 2022-12-19
Applicant(s): KLINIKUM DER TECHNISCHEN UNIVERSITÄT MÜNCHEN (TUM KLINIKUM)

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