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Deciphering tumor-promoting mechanisms mediated by neutrophils in vivo

Project description

Activating neutrophils against cancer

Activation of the immune system to fight cancer is a promising approach, but clinical efficacy has been limited. Current immunotherapy efforts focus mainly on T lymphocytes. The EU-funded CINPinCB project proposes neutrophils as an alternative cell therapeutic target as they are abundant in the tumour microenvironment. To investigate the complexity and heterogeneity of tumour-associated neutrophils, researchers propose to develop conditionally immortalised neutrophil progenitors as a cell source for experimental studies. The aim is to decipher the mechanisms that control the functions of these cells and generate new targets for immunotherapy.

Coordinator

UNIVERSITE DE GENEVE
Net EU contribution
€ 203 149,44
Address
Rue Du General Dufour 24
1211 Geneve
Switzerland

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Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Higher or Secondary Education Establishments
Other funding
€ 203 149,44