The next generation of intestinal organoids for inflammatory bowel disease research
Inflammatory bowel disease (IBD) represents a spectrum of conditions that involve chronic inflammation of the digestive tract. The development of novel disease model platforms is essential for the understanding of fundamental mechanisms of the disorder. The EU-funded SYNMAT FOR ORGANOIDS project aims to develop the next generation of human intestinal organoids (HIOs) using microfluidics encapsulation in synthetic niches. This technology will enable the controlled mass production of HIOs for disease modelling, drug screening and regenerative medicine applications. The co-culturing of HIOs with immune cells and microbiota will recreate physiological conditions and provide the next generation of HIOs, which recapitulate the complex spectrum of IBD, bringing new insights into the aetiology of the disorder.
Fields of science
Call for proposalSee other projects for this call
Funding SchemeMSCA-IF-GF - Global Fellowships
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
30332 0420 Atlanta Ga
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