Objective The cost-efficient production of sustainably derived biochemicals and biofuels is a critical goal of modern biotechnology. Redox-biosynthetic pathways are fundamental in chemical manufacturing for establishing a bio-based economy. The sustainable regeneration and recycling of redox cofactors is a pre-requisite for the viable industrial exploitation of many described redox-biosynthetic pathways. These boundaries hamper the employment of cofactor-dependent biotransformations at large-scale production processes. To overcome these limitations, the main objective of this project, PIEZOZYMES, pushes the forefront of technology, pursuing novel biotechnological tools aimed at the efficient regeneration of redox cofactors powered by mechanical sources. Such progress will bring several advantages over the current cofactor-regeneration systems, where the traditionally employed biochemical, electrochemical and photonic sources will be replaced by mechanical ones. The resulting technology of this project will have valuable social impact, paving new pathways for the cost-efficient exploitation of cofactor-dependent enzymes as economically suitable biocatalysts in a plethora of industrial catalytic biotransformations. Fields of science engineering and technologyenvironmental engineeringwaste managementwaste treatment processesrecyclingengineering and technologymaterials engineeringcompositessocial scienceseconomics and businesseconomicsbioeconomynatural scienceschemical sciencescatalysisbiocatalysisengineering and technologyindustrial biotechnologybiomaterialsbiofuels Keywords Piezoelectric materials enzyme immobilization biocatalysis Programme(s) HORIZON.1.1 - European Research Council (ERC) Main Programme Topic(s) ERC-2021-STG - ERC STARTING GRANTS Call for proposal ERC-2021-STG See other projects for this call Funding Scheme ERC - Support for frontier research (ERC) Host institution UNIVERSIDAD DE ZARAGOZA Net EU contribution € 1 500 000,00 Address CALLE PEDRO CERBUNA 12 50009 Zaragoza Spain See on map Region Noreste Aragón Zaragoza Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 500 000,00 Beneficiaries (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSIDAD DE ZARAGOZA Spain Net EU contribution € 1 500 000,00 Address CALLE PEDRO CERBUNA 12 50009 Zaragoza See on map Region Noreste Aragón Zaragoza Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 500 000,00
