Objective
Many eukaryotes have more than two sets of chromosomes due to whole-genome duplication (WGD) and are called polyploids. WGDs explain many cases of speciation bursts and evolutionary inventions. Some evidence suggests an adaptive advantage of polyploids: the origins of many ancient WGDs correspond to the times of extreme climate change, and contemporary polyploids often occupy harsher environments compared to their ancestors. However, most new polyploids are not as lucky and rarely survive. To explain the cause, predict and manipulate this process, we need to understand the basic principles of polyploidy: (1) how it is triggered, (2) what enables the initial survival of newly formed polyploids, and (3) how they stabilize a population and become successful. My program will comprehensively cover all these aspects, from the functional and genetic levels to the evolutionary forces driving the entire process. I propose a cross-disciplinary approach to identify common polyploidy principles in plant and animal diploid-tetraploid species complexes: Arabidopsis lyrata, widespread plant in Northern Hemisphere, and Neobatrachus, burrowing frogs living in the Australian desert. The approach combines classic genetics with the latest genomics technologies and population genetics analysis of natural herbarium and museum collections across broad geographies. I will (1) expose genetic and environmental predispositions to polyploidy formation by mapping natural variation of the unreduced gametes rates; (2) reveal mechanics and genetics stabilizing meiosis in polyploids, comparing recombination and selection across ploidies; (3) uncover polyploid populations recovery processes after bottlenecks accompanying their origin by reconstructing introgression patterns. Deciphering the mechanisms leading to successful polyploidization across the plant and animal kingdoms will deliver groundbreaking advances relevant across biology, agriculture, and medicine.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences genetics heredity
- natural sciences biological sciences genetics chromosomes
- medical and health sciences clinical medicine embryology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2021-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80539 MUNCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.