Objective
Ambient temperature above or below a threshold can adversely affect plant growth and development, and even lead to death. The tightly regulated distribution of the hormone auxin throughout the plant body controls an impressive variety of developmental processes that tailor plant growth and morphology to environmental conditions. Although non-optimal ambient temperature can alter auxin transport, the precise nature of this alteration and the underlying molecular mechanisms remain enigmatic. Hence, the aim of HOT-AND-COLD is to dissect the molecular mechanisms involved in auxin transport and its downstream signaling upon temperature stress, down to the tissue and cell-type-specific level, focusing on the root of the model organism Arabidopsis thaliana. To achieve this aim, I will combine high-resolution imaging techniques integrated with a temperature-controlled stage system, mass-spectrometry-based phosphoproteomics, TRAP-seq and chemical screens in a multifaceted approach that has never been used for such a study in plant root systems. Using this approach, I expect to reveal: (i) the temperature-responsive phosphoproteome of membrane proteins; (ii) the link between changes in membrane fluidity and the dynamics of auxin transport components within the plasma membrane; (iii) cell-type-specific translatomes that orchestrate auxin transport upon temperature shock as well as in the gradual temperature stress response; and (iv) sensors and components of the signaling pathways controlling plant acclimation to temperature stress. Taken together, the fundamental knowledge obtained through this research will contribute to the mechanistic understanding of plant responses to the temperature variability that will accompany climate change. Such understanding is key for anticipating the impacts of climate variability on agricultural and natural ecosystems.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- natural sciences biological sciences ecology ecosystems
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2021-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
750 07 Uppsala
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.