The biofabrication of a 3D in vitro human oviduct model to study infertility and factors affecting embryo development

Project description

A 3D in vitro oviduct model

The oviducts or fallopian tubes connect the ovary to the uterus, transferring egg and sperm and providing a suitable environment for fertilisation. The first embryonic cell divisions take place at the oviduct, setting the stage for fetal development and health in adult life. However, there are no suitable 3D models to further study the molecular mechanisms underlying oviduct function. Funded by the European Research Council, the OviChip project aims to build a 3D in vitro model that recapitulates the structural and biological aspects of the oviduct. The key objective is to understand the selection of healthy sperm and the impact of epigenetic factors affecting embryogenesis.

Fields of science

• medical and health sciences › clinical medicine › gynaecology › reproductive medicine
• medical and health sciences › medical biotechnology › tissue engineering
• medical and health sciences › clinical medicine › obstetrics › fetal medicine
• medical and health sciences › basic medicine › pathology
• medical and health sciences › clinical medicine › embryology

Programme(s)

• HORIZON.1.1 - European Research Council (ERC) Main Programme

Topic(s)

• ERC-2021-STG - ERC STARTING GRANTS

Call for proposal

ERC-2021-STG

See other projects for this call

Funding Scheme

HORIZON-AG - HORIZON Action Grant Budget-Based

Coordinator

UNIVERSITEIT MAASTRICHT

Net EU contribution

€ 2 318 530,00

Address

Minderbroedersberg 4
6200 MD Maastricht
Netherlands

Region

Zuid-Nederland › Limburg (NL) › Zuid-Limburg

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00