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Brain mechanisms of conscious processing, from correlates to signatures

Project description

Insight into conscious processing

How does our brain process information during consciousness, and how when we are unconscious, for example, during sleep or anaesthesia? Most theories stipulate that conscious processing involves the cooperation of multiple sensory regions of the brain, while during unconsciousness, brain activity is localised in specific regions. Funded by the European Research Council, the CONSCIOUSBRAIN project aims to explore an alternative hypothesis that dissociates conscious processing from sensory perception and task execution. Researchers will follow a multidisciplinary approach to study brain dynamics alongside neuro-computational models of conscious processing. The work will unveil neural signatures associated with conscious processing that can be employed in the future for the diagnosis of non communicating patients.

Objective

When we are awake, part of the information processed by our brain becomes conscious, so that we can acknowledge and report it. Despite important advances, there is no consensus on what brain mechanisms underlie this phenomenon. According to some models, we become conscious of a stimulus when information gets integrated across different sensory areas; for other, conscious processing only arises when sensory representations are made available to the executive system. With this project I explore a third possibility: that the core mechanisms of conscious processing can actually be distinguished both from sensory and executive processes. Such experimental dissection is made possible by two new approaches developed by my team. The first approach allows detecting brain dynamics that are characteristic of conscious processing, independently of whether a task is required on the stimulus or not, thus dissociating conscious processing from executive functions. The second builds upon the “retro-perception” phenomenon, in which we trigger conscious access at an arbitrary latency after the disappearance of a stimulus, thus desynchronizing conscious access from sensory processing. I will jointly leverage these two approaches, through a wide range of complementary techniques: experimental psychology, functional MRI, electro and magneto encephalography, and human intracranial recordings. Experimentation will go hand in hand with the development of a major update to current neuro-computational models of conscious processing, to explore the computational properties of such core system for conscious processing. Finally this research should reveal much longed-for neural signatures of conscious processing. I will aim at operationalizing these signatures for the diagnosis of conscious access in non-communicating patients, and for starting the exploration of how a conscious stream emerges from these moment-to-moment conscious access events.

Host institution

UNIVERSITE PARIS CITE
Net EU contribution
€ 1 918 515,00
Address
85 BD SAINT GERMAIN
75006 Paris
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 1 918 515,00

Beneficiaries (1)