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Disrupting the Migraine continuum of care for resource constrained settings

Objective

Chronic migraine is defined as a headache persistent for more than 3 months or a severe headache persistent for more than 15 days within a month. It affects approximately 2% of the world population. The World Health Organization classifies severe migraine attacks as among the most disabling illnesses, comparable to dementia and quadriplegia. Treatments start with pharmaceutical drugs, which have contra-indications and severe side effects and often remain ineffective in chronic migraine patients. Injectable treatments like Botox and nerve blocks can be effective but require multiple sessions per year and also have undesirable effects. Treatments using neurostimulation products that deliver electrical pulses to the occipital nerve have been up to 80% effective but they are designed for the back not the neck which results in high rates of surgical revisions. This leaves the chronic migraine population severely underserved and in need of an innovative solution.
Our vision is fundamentally based on disrupting the continuum of care and referral pathway by creating a more effective non-surgical solution that reduces cost and risk and therefore increases accessibility to more physicians and patients.
The consortium will develop a novel platform for the treatment of chronic migraine that will be particularly applicable to resource restricted environments and targeting underserved patients. We are working on 4 elements working together seamlessly. 1) A neurostimulation implantable device 2) A wearable device that will power the implantable device. 3) A mobile app to control the implant. 4) A delivery catheter that reduces tissue trauma and training required for physicians.

Coordinator

UNIVERSITA DI PISA
Net EU contribution
€ 358 333,50
Address
Lungarno Pacinotti 43/44
56126 Pisa
Italy

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Region
Centro (IT) Toscana Pisa
Activity type
Higher or Secondary Education Establishments
Other funding
€ 358 333,50

Participants (6)

SENSICHIPS SRL
Italy
Net EU contribution
€ 481 250,00
Address
Via Delle Valli 46
04011 Aprilia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centro (IT) Lazio Latina
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 481 250,00
CROWDHELIX LIMITED
Ireland
Net EU contribution
€ 371 619,50
Address
Trinity House 7 Georges Quay
T12NAX0 Cork

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Southern South-East
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 371 619,50
Univerzitetni klinicni center Maribor
Slovenia
Net EU contribution
€ 557 291,00
Address
Ljubljanska Ulica 5
2000 Maribor

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Region
Slovenija Vzhodna Slovenija Podravska
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 557 291,00
BRAI3N
Belgium
Net EU contribution
€ 458 733,00
Address
Jemappesstraat 5
9000 Gent

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 458 733,00
SKEIN-UKRAINE
Ukraine
Net EU contribution
€ 513 333,00
Address
18 Pyrohovskogo St
03037 Kyiv

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 513 333,00
CAPRI MEDICAL LIMITED
Ireland
Net EU contribution
€ 1 772 760,00
Address
55 Lansdowne Park
D04W2K0 Ballsbridge

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 1 772 760,00

Partners (3)

EUROPEAN SOCIETY OF REGIONAL ANAESTHESIA AND PAIN THERAPY
Switzerland
Net EU contribution
€ 0,00
Address
Rue Daubin 7
1203 Geneve

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Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Research Organisations
Other funding
No data
SOUTH TEES HOSPITALS NHS FOUNDATION TRUST
United Kingdom
Net EU contribution
€ 0,00
Address
Marton Road
TS4 3BW Middlesbrough

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Region
North East (England) Tees Valley and Durham South Teesside
Activity type
Research Organisations
Other funding
No data
CENTRE FOR PROCESS INNOVATION LIMITED LBG
United Kingdom
Net EU contribution
€ 0,00
Address
Wilton Centre Wilton
TS10 4RF Redcar Cleveland

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Region
North East (England) Tees Valley and Durham South Teesside
Activity type
Research Organisations
Other funding
No data