Objective Chronic migraine is defined as a headache persistent for more than 3 months or a severe headache persistent for more than 15 days within a month. It affects approximately 2% of the world population. The World Health Organization classifies severe migraine attacks as among the most disabling illnesses, comparable to dementia and quadriplegia. Treatments start with pharmaceutical drugs, which have contra-indications and severe side effects and often remain ineffective in chronic migraine patients. Injectable treatments like Botox and nerve blocks can be effective but require multiple sessions per year and also have undesirable effects. Treatments using neurostimulation products that deliver electrical pulses to the occipital nerve have been up to 80% effective but they are designed for the back not the neck which results in high rates of surgical revisions. This leaves the chronic migraine population severely underserved and in need of an innovative solution. Our vision is fundamentally based on disrupting the continuum of care and referral pathway by creating a more effective non-surgical solution that reduces cost and risk and therefore increases accessibility to more physicians and patients.The consortium will develop a novel platform for the treatment of chronic migraine that will be particularly applicable to resource restricted environments and targeting underserved patients. We are working on 4 elements working together seamlessly. 1) LUNA-AIR: An implantable electronics device with neural write stimulation 2) LUNA-CONTROL: A wearable device that will communicate with and power the implantable device. 3) LUNA-APP; a mobile app to control the implant. 4) LUNA-INJECT; an ergonomic, minimally invasive, injection device that minimises tissue trauma and training required for physicians. Fields of science natural sciencescomputer and information sciencesinternetinternet of thingsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsmedical and health sciencesbasic medicineneurologydementia Keywords Migraine Programme(s) HORIZON.2.1 - Health Main Programme HORIZON.2.1.5 - Tools, Technologies and Digital Solutions for Health and Care, including personalised medicine Topic(s) HORIZON-HLTH-2021-TOOL-06-01 - Smart medical devices and their surgical implantation for use in resource-constrained settings Call for proposal HORIZON-HLTH-2021-TOOL-06 See other projects for this call Funding Scheme IA - Innovation action Coordinator UNIVERSITA DI PISA Net EU contribution € 358 333,50 Address Lungarno pacinotti 43/44 56126 Pisa Italy See on map Region Centro (IT) Toscana Pisa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,25 Participants (6) Sort alphabetically Sort by Net EU contribution Expand all Collapse all SENSICHIPS SRL Italy Net EU contribution € 481 250,00 Address Via delle valli 46 04011 Aprilia See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Centro (IT) Lazio Latina Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 206 250,00 CROWDHELIX LIMITED Ireland Net EU contribution € 371 619,50 Address Trinity house 7 georges quay T12NAX0 Cork See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Southern South-East Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 159 265,50 Univerzitetni klinicni center Maribor Slovenia Net EU contribution € 557 291,00 Address Ljubljanska ulica 5 2000 Maribor See on map Region Slovenija Vzhodna Slovenija Podravska Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,25 BRAI3N Belgium Net EU contribution € 458 733,00 Address Jemappesstraat 5 9000 Gent See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 196 600,75 SKEIN-UKRAINE Ukraine Net EU contribution € 513 333,00 Address 18 pyrohovskogo st 03037 Kyiv See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 220 000,75 CAPRI MEDICAL LIMITED Ireland Net EU contribution € 1 772 760,00 Address 55 lansdowne park D04W2K0 Ballsbridge See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 759 755,00 Partners (3) Sort alphabetically Sort by Net EU contribution Expand all Collapse all EUROPEAN SOCIETY OF REGIONAL ANAESTHESIA AND PAIN THERAPY Switzerland Net EU contribution € 0,00 Address Rue daubin 7 1203 Geneve See on map Region Schweiz/Suisse/Svizzera Région lémanique Genève Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SOUTH TEES HOSPITALS NHS FOUNDATION TRUST United Kingdom Net EU contribution € 0,00 Address Marton road TS4 3BW Middlesbrough See on map Region North East (England) Tees Valley and Durham South Teesside Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CENTRE FOR PROCESS INNOVATION LIMITED LBG United Kingdom Net EU contribution € 0,00 Address Wilton centre wilton TS10 4RF Redcar cleveland See on map Region North East (England) Tees Valley and Durham South Teesside Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
