SELINA aims at providing robust methodologies, information and guidance for evidence-based decision-making that supports the protection, restoration and sustainable use of ecosystems and their services. The project employs 15 Demonstration Projects of private and public section decision-making at different levels and contexts. The upscaling of the outcomes of these projects, together with the establishment of Communities of Practice shall enable transformative change in EU member states. SELINA brings together experts from all 27 EU member states, associated countries (Norway, Switzerland, Israel, UK) and selected EU Overseas Regions with stakeholders from various public and private sectors. The expertise in the Consortium includes leading experts (ecologists, economists, social scientists) on Ecosystem Services (ES) science, ecosystem accounting and on science-policy-business interfaces from related actions (e.g. OpenNESS, ESMERALDA, MAIA, MAES, IPBES) that can succesfully carry out the defined transdisciplinary tasks. The involvement of these different scientific disciplines, including social sciences, is mandatory when dealing with complex human-environmental systems and questions of sustainability. The Project could start its actions straight-away and successfully address the call’s challenges, provide applicable tools and state-of-the-art models together with the comprehensive Compendium of Guidance on how to use the project outcomes in various integrated ES assessment contexts. The Project delivers real cases for evidence-, ES-based and harmonised decision-making across Europe, enabling transformative change to halt biodiversity decline and to secure the sustainable supply and use of essential ES.