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AnBioLED Ancestral Fluorescent Proteins as Biophosphors for Light-Emitting Diodes

Objective

Light Emitting Diodes (LEDs) are present in displays of the great majority of devices we use every day, including smartphones, computers, TVs, etc. Unfortunately, they use toxic non-renewable rare-earth materials for their functioning. Fluorescent Proteins (FPs) have already proven to be an eco-friendly alternative, but their performance over time decreases as the intensity of the excitation source increases. This is because FPs have not been naturally or artificially evolved to function as color converters in electronic devices. Since it is not possible to artificially evolve proteins under LED operation conditions (stress), AnBioLED proposes to merge through machine learning evolutionary information (Ancestral Sequence Reconstruction) and computational protein design to identify key mutations in order to improve FPs photo and thermal stability. More importantly, AnBioLED will use experimental results under device operation conditions to reinforce the protein design strategy. The new ancestral FPs will merge the excellent photoluminescence properties of existing FPs with the robustness of their ancestors. AnBioLED novel approach will allow for the first time to optimize existing FPs for LEDs applications.

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2021-PF-01

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Coordinator

TECHNISCHE UNIVERSITAET MUENCHEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 173 847,36
Address
Arcisstrasse 21
80333 Muenchen
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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