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Liposomes as nanoreactors for the bottom-up assembly of supramolecular structures in confined space

Objective

Nanoreactors are attractive systems for emerging technologies because they allow the manipulation of matter on a molecular scale to fabricate macroscale products. Consequently, nanoreactors have been used to carry out molecular synthesis and catalysis, where such processes are controlled and stimulated by confined space. However, the current nanoreactors suffer from a lack in the flow-control of substrate that can access their interior and they have not been used to build large supramolecular structures. To overcomes these disadvantages and improve the application of nanoreactors, in this project we propose a novel design of a nanoreactor based on the combination of liposomes and molecular transporters (LipoNanoReactors). We envisage that by a controlled transport of ions (metal cations or organic anions) through phospholipid membranes, we will be able to build supramolecular structures inside liposomes, where the final structure could be modulated by the rate of ion flow and confinement effects. As a result, this strategy will allow us to control the physical and chemical properties of such structures on a nanometric scale. Further than achieving supramolecular assembly inside liposomes, the present proposal looks to facing challenges as supramolecular isomerism, crystalline phase purity, and particle size control. Accordingly, this project opens new horizons in the field of crystal engineering, solid-state chemistry, and material sciences.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2021-PF-01

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Coordinator

UNIVERSITE LIBRE DE BRUXELLES
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 175 920,00
Address
AVENUE FRANKLIN ROOSEVELT 50
1050 Bruxelles / Brussel
Belgium

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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