Objective
L-Cell is a method for robust, reconfigurable control of surface topography, based on creating reversible light-induced surface structures onto azobenzene-containing bilayers. These light-reconfigurable substrates allow free-form topographical patterns to be created and subsequently erased over many cycles on a biocompatible cell culture substrate, even when the cells are already growing on the substrate. L-Cell aims at mimicking more closely the dynamic conditions in human body, which regulate many physiological and pathological processes, such as tissue morphogenesis, healing, and tumour growth. Our non-invasive solution is important for definition of chrono-programmes e.g. cell differentiation, stem cell phenotype harvesting, tissue regeneration and triggering cell directional migration. The bilayer structure allows for easy chemical modification of the surface, ensuring biocompatibility and further functionalization, and fully supporting existing protein deposition techniques. L-Cell reconfigurable light-responsive petri dishes can be used as drop-in solution, enabling new, unique biological investigations on cell dynamics to be conducted. Besides, the growing need to reduce animal testing in drug screening, toxicology, and research has increased the demand for innovative cell culture solutions that recapitulate the complexity of cell dynamics in a controllable, cost-effective way, without sacrificing their clinical relevance. For all these reasons, L-Cell offers new opportunities as an innovative tool for a wealth of potential targets.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences astronomy planetary sciences planetary geology
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine toxicology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2022-POC1
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
33100 TAMPERE
Finland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.