Objective
Metabolomics provides a real-time view of the metabolic state of the examined samples. The past decade the field showed strong growth, however limitations intrinsic to the field hinder further application in epidemiology level. Key obstacles include: variety of analyte molecular structures, slow marker identification, large differences in concentrations, poor validation, incomplete combination of data from different analyses and fragmentation of research. The consortium brings together scientists from different complementary disciplines and sectors to collaborate and set a research training network, combining infrastructure experience, knowledge and skills. The research scope is to identify the source of problems that hinder development, and recommend measures to overcome these. Training through
research will promote a new generation of omics researchers. Networking, joining forces via secondments will enhance research productivity transfer of knowledge. The project will train 10 ESRs in work-packages aiming toward improvement of design of experiment, harmonization of analytical methods, improved Data Mining and biochemical pathway analysis and translational research. Application will be in the study of blood metabolome of exhaustive physical exercise.
We aim to study sample stability & preparation (including blood and alternative forms such as dried blood spots), biomarker identification, exploitation of multiple datasets, promote standard procedures, develop robust pipelines, develop and implement machine searchable notations of metadata, central database for data storage, compare datasets, automate cross-laboratory data combination, develop novel algorithms for multidimensional data mining and reconstruct biochemical pathways. The overall goal is to train the ESRs in cutting edge metabolomics research and at the same time provide proof of concept of democratizing metabolomics by the use of patient centric sampling.
Fields of science
Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral NetworksCoordinator
546 36 THESSALONIKI
Greece
See on map
Participants (6)
28040 Madrid
See on map
85764 Neuherberg
See on map
07743 JENA
See on map
39100 Bolzano
See on map
75007 Paris
See on map
71800 Siilinjarvi
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partners (15)
Participation ended
WA15 9AF Hale Altrincham
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
153 41 AGIA PARASKEVI
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
54623 Tsessaloniki
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
145 65 Athens
See on map
80333 Muenchen
See on map
70211 KUOPIO
See on map
31062 Toulouse Cedex 9
See on map
07745 Jena
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
171 45 Solna
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
28359 Bremen
See on map
10115 Berlin
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
SW7 2AZ LONDON
See on map
81671 München
See on map
551 33 Kalamaria
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
MK8 0AB Milton Keynes
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.