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Towards new treatments of psychiatric disorders - a systems-oriented approach

Objective

The TrePsy project aims to integrate the Maj Institute of Pharmacology of the Polish Academy of Sciences (IP PAS) with leading European brain research centres in development of novel treatments of psychiatric disorders, strengthen research excellence at the IP PAS, and empower it to become leader in other Horizon Europe projects. To this end we will create a unique advanced research curriculum for students and early-career scientists, who will lead future neuropharmacological research, and form a cluster of institutions of excellence in the fields of Neuropsychopharmacology. The project will provide students, and PhD programme participants at the Maj Institute of Pharmacology of the Polish Academy of Sciences (IP PAS), as well as partner Institutes, with lectures and training in emerging topics and research methodologies. These activities will be organised through four advanced schools, each including lectures and hands-o training in advanced research methods, and additionally a “University Specialist” course that will be developed by the consortium. The training activities will be complemented with participation in regional science outreach events, with presentations focused on brain research, the importance of Neuropsychopharmacology-driven research. Furthermore, as an exploratory research project, we selected the study of neuronal and molecular mechanisms involved in the actions of cannabidiol. Each of the partners will contribute their unique research competence including transgenic mice and rats, a ‘multiome’ approach to gene regulation analysis with RNA-Seq and ATAC-Seq, advanced methods of imaging and controlling neuronal activity in behaving animals, and multimodal neuroimaging methodology. The planned research activities emphasize mutual benefits for all consortium partners, nevertheless, interactions with the three leading European research centres will have the greatest impact on research excellence at the IP PAS.

Coordinator

INSTYTUT FARMAKOLOGII IM. JERZEGO MAJA POLSKIEJ AKADEMII NAUK
Net EU contribution
€ 483 720,00
Address
Ul. Smetna 12
31 343 Krakow
Poland

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Region
Makroregion południowy Małopolskie Miasto Kraków
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (3)

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 288 750,00
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT
Germany
Net EU contribution
€ 280 500,00
Address
Square J 5
68159 Mannheim

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Region
Baden-Württemberg Karlsruhe Mannheim, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
Spain
Net EU contribution
€ 286 235,00
Address
Avenida De La Universidad S-n
03202 Elche

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Region
Este Comunitat Valenciana Alicante/Alacant
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00