DEVELOPING TRUSTWORTHY ARTIFICIAL INTELLIGENCE (AI)-DRIVEN TOOLS TO PREDICT VASCULAR DISEASE RISK AND PROGRESSION

Project Information

VASCUL-AID

Grant agreement ID: 101080947

DOI

10.3030/101080947

EC signature date 24 April 2023

Start date 1 May 2023

End date 30 April 2029

Funded under

• Health

Total cost

€ 5 969 125,00

EU contribution

€ 5 969 125,00

Coordinated by

STICHTING AMSTERDAM UMC
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (8)

Submission package RETRO-VASCULAID-AAA clinical DATA study

Submission package RETRO-VASCULAID-AAA clinical DATA study (ethical approval, final study protocol, registry nr) prior to first enrolment.RETRO-VASCULAID-AAA clinical DATA study: retrospective data collection of 5000 patients at clinical partners (Annex Clinical Studies).

Protocol and SOPs for collection of data for each data type

Protocol and SOPs for collection of data (medical images and pathological analysis) for each data type

A functional design describing the architecture and data flows that will be forming the apps

A functional design describing the architectureand data flows that will be forming the apps will be delivered.

Submission package PRO-VASCULAID-AAA clinical DATA study

Submission package PRO-VASCULAID-AAA clinical DATA study (ethical approval, final study protocol, registry nr, national authorities) prior to first enrolment.PRO-VASCULAID-AAA clinical DATA study: prospective data collection of 350 patients (phase I) at clinical partners (Annex Clinical Studies).

Submission package RETRO-VASCULAID-PAD clinical DATA study

Submission package RETRO-VASCULAID-PAD clinical DATA study (ethical approval, final study protocol, registry nr) prior to first enrolment.RETRO-VASCULAID-PAD clinical DATA study: retrospective data collection of 6000 patients at clinical partners (Annex Clinical Studies).

Standardised set of parameters to evaluate data outcome measurements

Standardised set of parameters defined to evaluate the data outcome measurements.

Project management handbook, month 1

Periodic reports with templates (no deliverable) as instructed by the PO.

Submission package PRO-VASCULAID-PAD clinical DATA study

Submission package PRO-VASCULAID-PAD clinical DATA study (ethical approval, final study protocol, registry nr, national authorities) prior to first enrolment.PRO-VASCULAID-PAD clinical DATA study: prospective data collection of 420 patients (phase I) at clinical partners (Annex Clinical Studies).

Other (5)

HELSI AI framework updates (M12)
Trustworthy AI in healthcare procedures: guidelines (M12)
A secure and redundant SaaS platform to host the apps

A secure and redundant SaaS platform to hostthe apps is established.

PAA segmentation algorithm established
Aorta segmentation algorithm established

Data Management Plan (1)

Data management plan

Ethics Requirements (1)

AI - OEI - Requirement No. 1

Ethics report of External Ethics Advisor:Due to sensitivity of the use of AI as a decision-making tool, an External Independent Ethics Advisor must be appointed to support the beneficiaries to identify the ethical concerns. An ethics report by the ethics advisor must be submitted at M3 with a view to the first ethics check. Details must be provided regarding AI decision-making support tool, and notably on human agency aspects of the involved clinicians. European Commission guidelines on AI can be found at the following link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ethics-by-design-and-ethics-of-use-approaches-for-artificial-intelligence_he_en.pdf The European Commission Guidance for Ethics Advisors/Boards can be found in the FTOP at the following link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/roles-and-functions-of-ethics-advisory-ethics-advisory-boards-in-ec-funded-projects_he_en.pdf.

Websites, patent fillings, videos etc. (3)

Communication, Dissemination and Exploitation plan
Website VASCUL-AID online
Social media accounts online

Publications

Peer reviewed articles (3)

Global Control for Local SO(3)-Equivariant Scale-Invariant Vessel Segmentation

Author(s): Patryk Rygiel, Dieuwertje Alblas, Christoph Brune, Kak Khee Yeung, Jelmer M. Wolterink
Published in: arXiv Computer Vision and Pattern Recognition, Issue 2024.15314, 2024, ISSN 2331-8422
Publisher: arXiv Computer Vision and Pattern Recognition
DOI: 10.48550/arXiv.2403.15314

International Consensus on Core Outcomes in Vascular Surgery: A Delphi Study Protocol

Author(s): Sabrina Zwetsloot, Lotte Rijken, Stefan Smorenburg, Venkat Ayyalasomayajula, Vincent Jongkind, Kak Khee Yeung
Published in: SSRN, Issue 4947551, 2024, ISSN 1556-5068
Publisher: SSRN
DOI: 10.2139/ssrn.4947551

SIRE: scale-invariant, rotation-equivariant estimation of artery orientations using graph neural networks

Author(s): Dieuwertje Alblas, Julian Suk, Christoph Brune, Kak Khee Yeung, Jelmer M. Wolterink
Published in: arXiv Computer Vision and Pattern Recognition, Issue 2311.05400, 2023, ISSN 2331-8422
Publisher: arXiv
DOI: 10.48550/arXiv.2311.05400

Book chapters (1)

Implicit Neural Representations for Modeling of Abdominal Aortic Aneurysm Progression

Author(s): Dieuwertje Alblas, Marieke Hofman, Christoph Brune, Kak Khee Yeung, Jelmer M. Wolterink
Published in: Lecture Notes in Computer Science, Functional Imaging and Modeling of the Heart, 2023, ISSN 1611-3349
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-35302-4_37