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Proteomic optimization of methods for ancient skeletal elements

Objective

Palaeoproteomics has the potential to resolve some of the big questions in palaeoanthropology and human evolution, as proteins have been found to preserve over long time periods in the archaeological record, and contain phylogenetically relevant information. However, as this is a relatively new field of research, method optimization and gaining further understanding of ancient proteomes is necessary, to gain robust and reliable results with minimal destruction to rare ancient fossils. To this end, PROMISE (PRoteomic Optimization of Methods for ancIent Skeletal Elements) aims to improve palaeoproteomic analyses by developing and thoroughly assessing methods for removing modern contamination from ancient specimens, releasing proteins from the mineral matrix of bones and teeth, and understanding the effect that postmortem microbial bioerosion has on ancient skeletal proteomes. Finally, these optimised methods will be applied to study Middle and Late Pleistocene Levantine hominins. The Levant is essential for understanding human migration out of Africa, as well as interactions between different contemporaneous hominin populations, but is a challenging area of study for ancient DNA, warranting further palaeoproteomic method development. PROMISE will advance methods for the entire field of palaeoproteomics, as well as the study of human evolution. PROMISE will be conducted in a dynamic international research environment, providing the fellow with essential skills setting them up for a successful future career as a researcher in archaeological science.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2022-PF-01

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Coordinator

KOBENHAVNS UNIVERSITET
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 214 934,40
Address
NORREGADE 10
1165 KOBENHAVN
Denmark

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
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Total cost

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No data

Partners (1)

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