Project description
Advanced biomaterials for load-bearing tissue regeneration
Musculoskeletal conditions impair mobility and dexterity, reducing the quality of life of patients and their ability to work. Tissue engineering and regenerative medicine offer potential solutions to restore functional tissues by combining cells and biomaterials. However, current biomaterials lack the mechanical strength required for load-bearing applications. With the support of the Marie Skłodowska-Curie Actions programme, the BigelInk project will develop a novel biomaterial that replicates the mechanical properties of native load-bearing tissues. The innovative biomaterial incorporates a colloidal two-component nanoparticle system with interpenetrating phases that make it simultaneously tough and flexible. Researchers hope to generate a safe and innovative platform for regenerative therapies and future clinical applications in musculoskeletal tissue repair.
Objective
Musculoskeletal conditions impact the patient’s mobility and dexterity. This greatly affects the patient’s ability to work and their overall quality of life. This burden could be lifted by tissue engineering and regenerative medicine solutions, which utilizes a combination of biomaterials and cells to restore functional tissues. Current biomaterials do not provide the strength needed for use in load-bearing applications as those seen in musculoskeletal conditions. BigelInk will develop a novel biomaterial formulation that mimics the mechanical properties of the native scaffolding of load-bearing tissues. It will do this by the design of a colloidal bigel, a two-component nanoparticle system with interpenetrating phases that is both tough and soft. The developed biomaterial will be tested for its biocompatibility according to world standards to enable further clinical trials. The biomaterial generated in this project will thereby provide a novel platform for tissue regeneration of load-bearing tissues.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been human-validated.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been human-validated.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
6525 GA NIJMEGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.