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Visible-light-activated transmembrane transport by photosensitized isomerization of stiff-stilbene based anion receptors

Objective

Stimuli-responsive transmembrane anion transport proteins are essential for cellular life due to their implication in important biological functions. Supramolecular systems with analogous properties have been developed, however, most of them rely on the use of damaging UV light. SENSiTRANS is an ambitious and multidisciplinary project aimed at activation of anion transporters using visible light by means of a sensitization strategy. The project focuses on the employment of photosensitizers able to trigger isomerization of stiff-stilbene based receptors in the lipid bilayer, allowing activation of passive transmembrane transport. In addition, insertion of the photosensitizer in a vectorial manner into the lipid bilayer will be explored towards light-driven active transport. The project will result in i) the development of a new strategy to control transmembrane transport with transformative impact in the field of molecular photoswitches and anion receptor chemistry, ii) preparation and growth of the fellow towards a fully independent academic career (the new scientific research skills, complementary soft skills and scientific connections she will acquire will provide her with the necessary competencies to access an academic position at an European institution), and iii) benefit from her multidisciplinary scientific background and her scientific network by the hosting group.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2022-PF-01

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Coordinator

UNIVERSITEIT LEIDEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 187 624,32
Address
RAPENBURG 70
2311 EZ Leiden
Netherlands

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Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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