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Deep brain stimulation based on the wireless magnetically localised and ultrasonically actuated micro-robot

Objective

The application of deep brain stimulation (DBS) is a significant neurosurgical breakthrough that allows targeted circuited-based neuromodulation, which can directly measure pathological brain activity and deliver adjustable stimulation for the management of neurological and psychiatric disorders correlated with dysfunctional circuitry. Traditional DBS systems, as the standard of care in Parkinson's disease, essential tremor and dystonia, are developed based on the cardiac field, including an intracranial electrode, an extension wire and a pulse generator, with advances in engineering and imaging technologies in the past two decades. However, these devices are typically centimetre-scale, which increases the risk of haemorrhage, infection and damage during the treatments. Instead, the small and remotely powered systems may result in less invasive neuromodulation. Therefore, the proposed research aims to develop a novel micro-robot that can implement deep brain stimulation by using the piezoelectric effect induced by ultrasound stimulation in the cerebral spinal fluid. The proposed biocompatible robot can achieve less invasive neuromodulation and precise positioning by using the wireless external magnetic field.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2022-PF-01

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Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 173 847,36
Address
HOFGARTENSTRASSE 8
80539 MUNCHEN
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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