Objective
The overarching scientific goal of the LIGHTSUPGEL study is to design and synthetize novel reversible photo-switchable azobenzene and bis(urea)-based supramolecular gels, and to develop a super-resolution microscopy-based methodology to visualize the self-assembly and disassembly process in real-time with the aim of unravelling their underlying mechanisms. The cutting-edge combination of super-resolution STED and FLIM microscopies, together with environment-sensitive fluorescent probes, will be employed to spatially controlled photo-switch the gelation and de-gelation, and for first time, simultaneously monitor the process with nanoscopic resolution. Furthermore, the application of this new knowledge and novel photo-switchable gels in gel-mediated drug crystallization, will be explored. The possibility of light-triggered drug crystal harvesting photo-switchable gels offers, will be the first ever described non-invasive and reversible method to harvest crystals from gels. This new technology will mean a huge advance in the field of gel-phase drug crystallization, bringing it closer to its industrialization. By completing this ambitious multidisciplinary work, the applicant will be in an excellent position to create cross-disciplinary collaborations with research groups and industry across Europe and to becoming an independent researcher himself.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
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Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinator
18071 Granada
Spain