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Decellularised Extracellular Carpets for the Innovative Production of Human Engineered Replicates

Project description

Cell-derived products to enhance biotech industry competitiveness

The main challenge in commercialising cell-derived products is the lengthy ex vivo culture period. Macromolecular crowding (MMC) can accelerate biochemical reactions, expediting the development of these products. The ERC-funded DECIPHER project aims to leverage MMC to advance cell-derived product development through two technical and three commercial work packages. This will strengthen the international competitiveness of European biotech industries while generating job opportunities, markets, and revenue streams. As an interdisciplinary and intersectoral effort, the project will also provide training for a postdoctoral researcher at the forefront of scientific research and technological innovation. Hosted by University College Dublin, the project will contribute to advancements in the field.

Objective

The major roadblock in the commercialisation of cell-derived products is the prolonged ex vivo culture period required to develop them. Macromolecular crowding (MMC), a biophysical phenomenon that increases the kinetics of biochemical reactions and biological processes by several orders of magnitude, allows for the accelerated development of cell-derived products. This project will exploit MMC in the development of cell-derived products in 2 technical and 3 commercial work-packages, increasing the international competitiveness of European-based biotech industries and creating new employment, markets and revenue. This 18-months interdisciplinary and intersectoral project will train 1 post-doctoral researcher at the forefront of scientific research and technological innovation. The project will be carried out at University College Dublin, Ireland’s largest university, one of Europe’s leading research-intensive universities and in the top 1 % universities world-wide.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2023-POC

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Host institution

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (1)

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