Objective
The proposed research seeks to advance the state of the art in skin cancer diagnostics by developing an electrochemical sensor for tumour markers (or biomarkers) utilizing hierarchical nanoengineered assemblies of titania (Hi-NEAT) nanoparticles. Melanoma is the most aggressive and deadliest form of skin cancer that can spread quickly to other body areas, so its early identification and treatment are vital. The existing histological and immunological cancer detection techniques are intricate, expensive, and often lack sensitivity and specificity. Therefore, in this project, we intend to introduce a subtle, rapid, accurate, facile, and low-cost Hi-NEAT-based electrochemical sensor to detect the biomarker tyrosinase, a crucial enzyme involved in melanin overproduction and development of skin melanoma. The following two research goals have been set forth to achieve this: 1) Creation of Hi-NEAT nanoparticles with enhanced electrocatalytic activity towards tyrosinase via tuning their physicochemical/surface properties and 2) Employing large-scale facilities (synchrotron/neutron sources) to investigate the interfacial properties of the titania-tyrosinase interaction. Thus, the current project represents a groundbreaking approach to push the frontiers of skin cancer diagnosis through the innovative use of titania nanoparticles and large-scale facilities for developing an effective point-of-care electrochemical sensor. Success in this research promises heightened precision and sensitivity in melanoma detection, potentially leading to timely diagnoses and improved patient outcomes. Ultimately, we aspire to make a significant contribution to health care by lessening the severity of melanoma, reducing overall care expenses, and increasing the lifespan of cancer survivors in line with the European Commissions beating cancer plan.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology skin cancer melanoma
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- engineering and technology nanotechnology nano-materials
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
205 06 MALMOE
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.