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Genetics across the lifespan: Unraveling age-specific determinants of severe mental illness

Objective

Mental disorders affect 1 in every 8 people in the world right now. Genetic predisposition plays a crucial role in the development of severe mental disorders. Genome-wide association studies (GWAS) revolutionized the field of psychiatric genomics by identifying the individual effects of millions of common genetic variants on behavioral, cognitive, and clinical traits. However, current GWAS provide a static snapshot of genetic influences and thus misses the rich tapestry of genetic effects that unfold across an individual's lifespan. Funded by the Marie Skodowska-Curie Actions program, the GenLife project aims to uncover novel genetic variants with age-dependent effects that have remained hidden until now. Revealing age-specific determinants of severe mental illness across the lifespan will promote the development of more effective, biology-based prediction tools tailored to individuals' disease trajectories. By providing timely support and intervention, mental health professionals will be able to identify and address emerging mental health issues before they escalate into more severe conditions. The GenLife project is based on the synergy between the applicant's highly interdisciplinary profile, cutting-edge research at the host institution, and unique Nordic resources. It will be completed at world-leading research institutions, the University of Oslo and the Norwegian Centre for Mental Disorders Research (NORMENT), under the supervision of Prof. Ole A. Andreassen. Expanding the applicant's line of research, academic maturity, and professional networks will enhance the development of his career as an independent researcher.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2023-PF-01

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Coordinator

UNIVERSITETET I OSLO
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 226 751,04
Address
PROBLEMVEIEN 5-7
0313 Oslo
Norway

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Region
Norge Oslo og Viken Oslo
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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