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Twinning to skyrocket scientific excellence towards individual radiosensitivity prediction by raising the bar in knowledge transfer, networking, and technological innovation in radiobiology

Objective

Prostate cancer patients receiving radiotherapy (RT) may develop radiation-induced side effects, which significantly impact quality of life. One of the main challenges in radiobiology is to predict individual patient's normal tissue radiosensitivity to tailor personalized RT. Although the Institute for Oncology and Radiology of Serbia (IORS) is a highly specialized health, scientific, and educational institution it is necessary to develop a strategic action plan and sustainable knowledge transfer networking with top-class leading European institutions. Through the 6 Specific Objectives, RadExIORSBoost project aims to develop and implement institutional Scientific Strategy on radiobiology, to investigate individual radiosensitivity by transcriptome profiling, radiation-induced lymphocyte apoptosis, and measurement of DNA damage levels, to design a high-quality clinical study, and to raise the research capacity of IORS and partner institutions through 5 international workshops, 8 short-term visits, and 6 trainings. RadExIORSBoost project aims to strengthen the administrative and research management skills of IORS. RadExIORSBoost project realization will increase the scientific excellence of IORS to approach high-ranking partner institutions, Medical Faculty Mannheim, Heidelberg University (UHEI), Germany, the University of Leicester (ULEIC), United Kingdom, Medical University of Vienna, Center for Cancer Research, (MUW) Austria, and the Institute of Oncology Ljubljana (IOL) from Slovenia. Artificial intelligence-based models, such as machine learning may give directions towards the clinical application of peripheral blood mononuclear cell transcriptome, and list potential biomarkers predicting radiotoxicity, not only in cancer patients, but also in healthy individuals at risk. RadExIORSBoost project may blaze the trail for technological innovations in modern radiation oncology to significantly reduce the side effects of RT and its harmful effects on the environment.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-CSA - HORIZON Coordination and Support Actions

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-WIDERA-2023-ACCESS-02

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Coordinator

INSTITUT ZA ONKOLOGIJU I RADIOLOGIJU SRBIJE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 502 562,50
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (3)

Partners (1)

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