Project description
Bio-adaptive wave control technologies for deep-body bioelectronics
Wireless medical devices can be implanted to monitor health and deliver therapies. Technological advancements now enable minimally invasive, battery-free implants for health monitoring and nerve stimulation. A major challenge is effectively powering and controlling these devices from outside the body, due to the complexities of electromagnetic wave propagation in human tissue. The ERC-funded BESSEL project will develop bio-adaptive wave control technologies for efficient powering and precise control of millimetre- and micrometre-scale deep-body bioelectronics. The project will investigate wave behaviour in complex anatomical environments and create new conformal radiating surfaces for the practical implementation of these methodologies. It will also demonstrate clinical utility by wirelessly recording and modulating pancreatic nerve activity in an anaesthetised porcine model.
Objective
Wireless medical devices can be implanted in the body to monitor health and to deliver therapies. Recent advances in biosensors, neural interfaces, biotechnology, microelectronics, and improved surgical techniques enable a vision of minimally invasive battery-free bioelectronic implants that can perform a wide range of medical and research tasks. Examples include biosensing for an early detection of health anomalies, recording and precision stimulation of central and peripheral nervous systems, implantable labs-on-a-chip, surgical microbots, and so on. A key scientific challenge lies in how these devices can be powered and controlled from outside of the body. Existing wireless solutions remain limited in their ability to transfer energy and data. These limitations result from the difficulty in controlling electro-magnetic waves in the human body a dynamic, heterogeneous, and lossy medium. The objective of this proposal is to develop bio-adaptive wave control technologies that overcome these challenges to enable efficient powering and precise control of mm/m-scale deep-body bioelectronics. To accomplish this, we will (1) focus on the fundamental studies of waves and their control in complex and dynamic anatomical media; (2) develop new reconfigurable architectures of conformal radiating surfaces for the practical implementation of the developed wave control methodologies, and (3) demonstrate clinical utility by fully wireless recording and modulation of the pancreatic nerve activity in an anesthetized porcine model through dynamic wave control. The proposal relies on interdisciplinary track-record of the PI in bioelectronics and neural interfaces, wave physics and computational electromagnetics, conformal radiating structures and wireless power transfer. BESSEL consolidates these skills and enables conducting research on highly capable deep-body wireless bioelectronics with high translational potential.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensors
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Keywords
Programme(s)
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Topic(s)
Funding Scheme
HORIZON-ERC - HORIZON ERC GrantsHost institution
75794 Paris
France