Project description
Educating researchers about frailty for healthy ageing
Our society is ageing due to declining birth rates and longer life expectancy. While more people are living longer, the average adult spends the last 15-20 years in poor health. Frailty in old age contributes to this, increasing vulnerability to stressors like falls, surgeries, and infections. Consequently, there is a growing focus on improving the period of healthy living, known as healthspan. Supported by the Marie Skłodowska-Curie Actions programme, the UNION project will educate 13 early-stage researchers about frailty for healthy ageing. It involves experts from various disciplines and uses cutting-edge technologies applied to clinical settings. The project aims to address the challenges of our ageing society.
Objective
With falling birth rates and increasing life expectancy we are an ageing society. 20% of boys and 25% of girls born in 2019 are expected to reach their 100th birthday. This would be good news if it were not for the fact that healthy life span has not kept pace with increasing longevity and now on average adults spend the last 15-20 years of life in ill health. Frailty is a major component of ill health in old age and refers to an enhanced vulnerability to stressors, such as falls, surgery or infections, which was demonstrated clearly in the mortality data for the COVID19 pandemic. The transition from robust health to frailty is a critical factor in the loss of independence and places increased pressure on health and social care. All of this has led governments to prioritise the enhancement of healthspan.
The Doctorate Network on UnderstandiNg fraIlty tOwards a future of healthy ageiNg (UNION) is a multi-partner joint doctoral research training network with the overall aims of educating 13 Early Stage Researchers (DCs), advancing the current understanding of frailty, and providing innovative solutions on how healthy ageing can be achieved. UNION brings together world leaders in a range of relevant disciplines (frailty, ageing biology and ageing medicine, inflammation, immunosenescence, immunometabolism, stem cell biology) with state-of-the art technologies including mass spectrometry metabolomics, advanced imaging, artificial intelligence, CRISPR-CAS9 libraries, SPECTRA 35-colour flow cytometry, global and conditional knockout mice. This technological excellence is applied to the clinical situation through unique longitudinal human ageing and frailty cohorts, longitudinal assessment of age-related multimorbidity in animal models and innovative multidimensional frailty indices in humans. Together this integrated activity will provide the highest quality training and research environment in our rapidly ageing society.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- social sciencessociologydemographymortality
- medical and health sciencesclinical medicinesurgery
- medical and health scienceshealth sciencespublic healthepidemiologypandemics
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Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral NetworksCoordinator
20122 Milano
Italy
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Participants (7)
28049 Madrid
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20132 Milano
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20132 Milano
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17177 Stockholm
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28006 Madrid
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13125 Berlin
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50937 Koeln
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Partners (12)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
8020 Graz
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
14482 Potsdam
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
07981 Whippany
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1200 Bruxelles / Brussel
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
9000 Ghent
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
EC1V 2PT London
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
88662 Ueberlingen
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
28010 Madrid
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
WC1E 6BT London
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
B15 2TT Birmingham
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
50668 Köln
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
73100 Lecce
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