Project description
Smart sensor for early treatment of coronary artery disease
Coronary artery disease (CAD) is mainly due to plaque build-up in the arteries. While treatments such as balloon angioplasty and stenting are common, they can sometimes cause restenosis. There is a need for technologies to monitor and manage these CAD-related complications. Supported by the Marie Skłodowska-Curie Actions programme, the SMART-CAD project aims to develop a stent-based sensor that continuously monitors the arteries and enables early treatment of in-stent restenosis (ISR). This device will combine a microwave sensor to detect ISR with RFID technology for ongoing assessment of coronary artery health. If ISR is detected, microwave ablation will be used to treat the plaque directly. SMART-CAD contributes to the broader goal of reducing premature cardiovascular deaths across Europe by 2030.
Objective
In Europe, out of all types of cardiovascular diseases, coronary artery disease (CAD) is the most common cause of death (more than 40%). The leading cause of CAD is a blockage in the coronary artery due to plaque deposition. Balloon angioplasty and stenting are the two solutions used to treat CAD patients. However, in both treatments, restenosis (plaque re-deposition) occurs after a few months/years, and the only solution is to repeat the treatment to reopen the blocked artery. In the past, the scientific community has proposed many ways to monitor ISR; still, no research has suggested a feasibility study or stent-based treatment along with sensing and continuous monitoring. Motivated by the urgent need for new technological advancements to reduce the morbidity and mortality related to CAD (coronary artery disease), the proposed SMART-CAD project set out to develop a novel stent-based sensor for continuous sensing, monitoring and early treatment of the ISR (In-stent Restenosis). Here, a stent-based microwave sensor will be designed and implemented on the stent’s body to sense the development of the ISR, an RFID technology will assist in continuous monitoring of coronary artery health, and a microwave ablation will treat the plaque if ISR develops in the coronary artery. This will also help to boost the sustainable development goal target 3.4 (To reduce premature and preventable deaths in Europe due to cardiovascular diseases by 2030). The interdisciplinary nature of this project is strong, involving radiofrequency and microwave engineering, biomedical engineering, and biology. The results of this project will be helpful to the scientific community and medical device industry. This project will also strengthen the researcher’s academic profile and allow her to establish her own research group.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technologyelectrical engineering, electronic engineering, information engineeringinformation engineeringtelecommunicationsradio technologyradio frequency
- social sciencessociologydemographymortality
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
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Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinator
33100 Tampere
Finland