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Stent-based Sensing, Monitoring, And theRapy sysTem for Coronary Artery Diseases

Project description

Smart sensor for early treatment of coronary artery disease

Coronary artery disease (CAD) is mainly due to plaque build-up in the arteries. While treatments such as balloon angioplasty and stenting are common, they can sometimes cause restenosis. There is a need for technologies to monitor and manage these CAD-related complications. Supported by the Marie Skłodowska-Curie Actions programme, the SMART-CAD project aims to develop a stent-based sensor that continuously monitors the arteries and enables early treatment of in-stent restenosis (ISR). This device will combine a microwave sensor to detect ISR with RFID technology for ongoing assessment of coronary artery health. If ISR is detected, microwave ablation will be used to treat the plaque directly. SMART-CAD contributes to the broader goal of reducing premature cardiovascular deaths across Europe by 2030.

Objective

In Europe, out of all types of cardiovascular diseases, coronary artery disease (CAD) is the most common cause of death (more than 40%). The leading cause of CAD is a blockage in the coronary artery due to plaque deposition. Balloon angioplasty and stenting are the two solutions used to treat CAD patients. However, in both treatments, restenosis (plaque re-deposition) occurs after a few months/years, and the only solution is to repeat the treatment to reopen the blocked artery. In the past, the scientific community has proposed many ways to monitor ISR; still, no research has suggested a feasibility study or stent-based treatment along with sensing and continuous monitoring. Motivated by the urgent need for new technological advancements to reduce the morbidity and mortality related to CAD (coronary artery disease), the proposed SMART-CAD project set out to develop a novel stent-based sensor for continuous sensing, monitoring and early treatment of the ISR (In-stent Restenosis). Here, a stent-based microwave sensor will be designed and implemented on the stent’s body to sense the development of the ISR, an RFID technology will assist in continuous monitoring of coronary artery health, and a microwave ablation will treat the plaque if ISR develops in the coronary artery. This will also help to boost the sustainable development goal target 3.4 (To reduce premature and preventable deaths in Europe due to cardiovascular diseases by 2030). The interdisciplinary nature of this project is strong, involving radiofrequency and microwave engineering, biomedical engineering, and biology. The results of this project will be helpful to the scientific community and medical device industry. This project will also strengthen the researcher’s academic profile and allow her to establish her own research group.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

TAMPEREEN KORKEAKOULUSAATIO SR
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 242 116,80
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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