Project description
When fungal hybrids thrive – or fail
Trichaptum abietinum, a wood-decaying fungus, forms hybrids where distinct populations meet. While thriving in central Europe, it fails to establish in Norway. This raises a key question in evolutionary biology: what happens when species or divergent populations interbreed? Hybridisation can produce unfit or sterile offspring, but sometimes creates individuals with new traits that boost survival. As hybridisation is expected to increase with climate change and human activity, the FINESSE project explores its role in adaptation and speciation. Supported by the Marie Skłodowska-Curie Actions programme, FINESSE will sequence wild T. abietinum populations, create lab hybrids, and use CRISPR-Cas9 to identify the genetic factors behind hybrid success and failure.
Objective
Hybridisation, mating between distinct species or divergent populations, can lead to a variety of different outcomes. Many hybrid offspring will have low fitness or be inviable, while others may increase fitness under extreme conditions by producing transgressive hybrids with phenotypes outside of their parental range. The role of hybridisation in adaptation and speciation is a key question in evolutionary biology, especially as hybridisation is predicted to rise due to climate change and other human activities.
In FINESSE (Fungal INtrogrESsion and SpEciation) we aim to use the wood-decaying fungus Trichaptum abietinum as a study system for researching hybridisation. In Europe, there are three distinct populations of T. abietinum: a Mediterranean population, a Boreal, and an Atlantic population. Where populations overlap, there are different hybrid outcomes with hybrids found in central Europe but not Norway. These contrasting outcomes make our system ideal to study patterns of introgression and hybridisation in Europe.
During FINESSE we plan to 1) gather and sequence field samples from underrepresented regions across Europe, both to explore the diversity of these populations in Eastern Europe and identify the origin of the Atlantic population in Norway. 2) Generate hybrids in the lab to help us understand the differing hybrid outcomes found in Europe, and identify mechanisms of hybrid incompatibility through genomic and phenotypic assays. 3) Use a reverse genetics approach to identify genes associated with hybrid incompatibilities, using CRISPR-Cas9 transformation of candidate genes. I will also use the project to improve both my scientific and transferable skills by taking courses, from other researchers in the department, during management of the project, and more generally from working on the project. Overall, this project will let me gain the skills necessary to become a more independent researcher and improve my future career prospects.
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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(opens in new window) HORIZON-MSCA-2024-PF-01
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0313 Oslo
Norway
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