Objective
Venous thromboembolism (VTE) is a common and serious disease in which a blood clot forms in the venous system. When a blood clot forms in the deep veins of the leg (deep vein thrombosis, DVT) and migrates through the bloodstream, to lung arteries, it creates a pulmonary embolism (PE). VTE encompasses DVT and PE and causes more than 30000 annual deaths in Europe. After clinical investigation, nearly half of the events can be explained (immobilisation, cancer, inherited thrombophilia), the other half of VTE cases have no known origin (called idiopathic VTE). Among the patients developing idiopathic, about 30% of them would have a recurrent thromboembolic event, 70% would not be subjected to any recurrence.
This leads to difficult decisions in the population of idiopathic VTE; if the anticoagulation therapy used to treat VTE is very efficient it also has major side effects, such as bleeding events, that can be deadly. A balance must be struck between the risks of recurrent thrombosis if anticoagulant treatment is stopped versus the risks of bleeding associated with continued anticoagulation therapy that can go up to the course of decades.
Physico-chemical properties of clots seem to be relevant parameters to describe their mechanical resistance and to develop risk assessment models. Currently, the most investigated methods in the literature are based on turbidimetry, rheology and permeation. Therefore, the development of optical approaches seems particularly interesting. In addition to their ease of implementation, their non-invasive and non-contact features, they would allow access to information related to the clot density, fibrin fibre arrangement, and dynamic changes during clot formation. These techniques are promising, but an integration of the different results from various methods is necessary to get a comprehensive understanding of clot properties.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine angiology vascular diseases
- medical and health sciences clinical medicine oncology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
29200 BREST
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.