Project description
How heatwaves impact hypertensive individuals
Heatwaves raise the risk of hospitalisation and death for those with cardiovascular diseases. Although hypertension needs medication for control, some antihypertensive drugs may worsen dehydration during heatwaves. There are no clinical guidelines for managing hypertension in these conditions. Supported by the Marie Skłodowska-Curie Actions programme, the HEAT-UP project will investigate how heatwaves impact emergency hospital visits among individuals taking various antihypertensive medications. It will focus on the link between heatwaves and orthostatic hypotension, which can lead to dizziness, falls, and injuries. The project will also develop a heat vulnerability index to inform counselling for hypertensive patients in high-risk areas, using advanced causal inference methods and data from Dutch and French administrative and hospital databases.
Objective
Heatwaves have increased in frequency, duration, and intensity over the past decades, placing individuals with cardiovascular diseases at higher risk of hospitalisation and death. Hypertension affects a third of adults and is a key risk factor for these diseases. Blood pressure control through medication is essential to prevent adverse cardiovascular events during and between heatwaves. However, concerns arise that antihypertensive drugs may increase the risks of hospitalisation and mortality during heatwaves. Certain antihypertensive drugs or their combinations may worsen dehydration, inhibit thirst perception, and interfere with heat adaptation. There is a lack of clinical guidelines for hypertension management during heatwaves.
To address this, I propose the HEAT-UP project, which aims to use expertise from environmental epidemiology, clinical practice, urban planning, geography, and causal inference to i) measure how the causal effects of heatwaves on emergency hospital visits vary across individuals taking different antihypertensive drugs, ii) map how heatwaves contribute to orthostatic hypotension when standing blood pressure drops, potentially leading to dizziness and falls, injury, and death across people with different antihypertensive treatments, and iii) develop a heat vulnerability index to support counselling interventions for hypertensive patients in areas with overheating risk.
This project will integrate advanced causal inference methods (causal random forest, case time series) and complementary data sources (French, Dutch administrative databases, and hospital databases). The findings will inform stakeholders creating safe treatment guidelines for hypertensive patients during heatwaves, as well as improve monitoring in vulnerable areas with limited medical access. This project will broaden my scientific expertise (technical and transferable skills) and my international network for pursuing an academic career and becoming an independent researcher.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- natural sciences computer and information sciences databases
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- medical and health sciences health sciences public health epidemiology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75654 Paris
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.