Project description
Shaping living materials with thermal tweezers
Designing complex biomaterials (cells, organoids, artificial cells, and hydrogels) requires precise control across multiple scales. However, fabrication methods lack versatility and standardisation. Supported by the Marie Skłodowska-Curie Actions programme, the TE-PAMS project aims to develop a biocompatible thermal tweezer (Bio-TT) technique to manipulate materials with nanometric precision, enabling dynamic assembly and programmable design of engineered living materials (ELMs). By integrating particle manipulation with functionalised artificial cellular components, the project addresses key challenges in spatial-temporal control, automation, and standardisation. Ultimately, TE-PAMS is expected to advance biomaterials, tissue engineering, and synthetic biology, providing tools and knowledge for creating multi-scale, hierarchical living materials with tailored functions.
Objective
The proposed research aims to develop an innovative biocompatible thermal tweezer (Bio-TT) technique for the design of multi-scale, hierarchical biomaterials, including cells, organoids, artificial cells and hydrogels, to meet multiple performance criteria (e.g. dynamic assembly, multi-scale manipulation, and standardised control). To this end, a programmable design concept will be introduced, integrating a novel TT particle manipulation method with functionalised artificial cellular materials, specifically tailored for engineered living materials (ELMs). This proposal will, for the first time, address several technical challenges in the fabrication of ELMs, such as the versatility of multi-scale active materials, precise spatialtemporal manipulation, as well as issues of automation and standardisation in the ELMs assembley process. The applicant, in collaboration with the teams at Cardiff University, will deliver internationally recognised knowledge and techniques in the fields of biomaterials, fluid dynamics, synthetic biology engineering, tiisue engineering, and hybrid living mateirlas.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology industrial relations automation
- engineering and technology industrial biotechnology biomaterials
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
CF10 3AT CARDIFF
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.