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Advanced Sensing Platforms for Single-Cell Metabolic Flux Analysis in Heterogeneous Cell Systems

Objective

Accurately assessing hypoxia and acidosis in the tumor microenvironment is crucial for understanding tumor behavior and determining treatments effectiveness. These conditions, caused by uncontrolled cancer cell proliferation, are key indicators of aggressiveness and metastasis risk, yet remain difficult to measure precisely.
The HySENSE project addresses this gap with an innovative sensor kit capable of real-time, cell-specific measurements of oxygen and pH at high spatio-temporal resolution. This advanced technology surpasses current tools, offering deeper insights into tumor behavior and therapeutic effects.
HySENSE will be validated using patient-derived colorectal cancer models, and a business feasibility study will define the path to commercialization. By enabling precise analysis of hypoxia and acidosis, HySENSE aims to transform cancer diagnostics and treatment planning, ultimately improving patient care.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been validated by the project's team.

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2024-POC

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Host institution

CONSIGLIO NAZIONALE DELLE RICERCHE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 110 000,00
Address
PIAZZALE ALDO MORO 7
00185 Roma
Italy

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (2)

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