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The effects of sexual selection on epidemic outcomes

Objective

Sexual selection has two intuitive but overlooked implications for epidemics. First, infectious diseases spread when individuals contact each other. Reproduction is a major driver of contact: mate preferences should affect who contacts whom, and thus parasite transmission opportunity. Sexual selection research shows that choosers prefer mates with high quality ornaments, which generally indicate parasite resistance, but the predicted epidemiological consequence of such contact with more resistant individuals – that transmission slows – is untested. Second, choosers selecting mates that resist parasite infection may benefit indirectly as this increases the parasite resistance of their offspring. If choosers consistently produce offspring with the most genetically resistant mates, population-level parasite resistance should increase through generations: again, untested.

I will leverage essential existing knowledge and artificial selection lines of the Trinidadian guppy, its gyrodactylid parasites, and a successful workflow I have developed, to test how variation in female preference affects epidemics in three ways. First, I will run replicate experimental epidemics in groups of individually identified guppies, tracked using machine learning, in which females do, or do not prefer males with larger orange ornaments. These ornaments indicate parasite resistance in this system. Second, I will assay the offspring produced post-epidemic for parasite resistance and paternity. I predict that epidemics in which females prefer ornamented males will be slower, and the offspring produced will be more resistant to parasites. Finally, I will use the results from both experiments to refine a mathematical model. We will validate model predictions with surveys of natural populations known to vary in female preference for males with larger orange ornaments. The resulting framework of how sexual selection affects parasite transmission will improve our predictions of epidemic dynamics.

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Topic(s)

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HORIZON-ERC - HORIZON ERC Grants

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Call for proposal

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(opens in new window) ERC-2025-STG

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Host institution

STOCKHOLMS UNIVERSITET
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 499 262,00
Address
UNIVERSITETSVAGEN 10
10691 Stockholm
Sweden

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 499 262,00

Beneficiaries (1)

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