Project description
Digital twins of the lungs to improve outcomes in respiratory diseases
Digital twins of the lungs combine clinical data, physics and AI to create personalised computational models that accurately predict respiratory system behaviour in health and disease. This platform technology provides new and unique health intelligence across healthcare and life science applications. The EIC-funded Twinhale project advances and validates this innovation by providing the Twinhale tool to biotech, pharma and medtech companies. It enables in silico trials for pulmonary drug delivery, accelerating the development of safer and more effective inhaled therapies. This milestone represents a major business opportunity and lays the foundation for broader platform adoption across the medical value chain, from the discovery of new therapies to their clinical application.
Objective
Due to the limitedness of current technologies, the respiratory system has historically been a sort of black box in many aspects of R&D and clinical practice. At Ebenbuild we want to open this black box by building the first accurate, patient-specific simulation models of the lungs, the so-called digital twins of the lungs. In addition to patient data, these are based on first-of-a-kind predictive, physiologically accurate computational models of the respiratory system. By opening the black box for the very first time, our technology holds the potential to become the definitive source of health intelligence for respiratory diseases across a variety of use cases in healthcare and life sciences, from preclinical R&D to point-of-care. This will make Ebenbuild a deep-tech vanguard with a diversified spectrum of scalable products, each with a significant patient benefit and a global revenue potential and with our technological platform at their core.
With EIC support we aim at expanding and validating the potential of our technology for provision of Twinhale tool to Biotech, MedTech and Pharma companies. Twinhale supports in-silico trials for pulmonary drug delivery and enables faster development of better inhalable treatments. Achieving this milestone will not only unlock an intriguing business opportunity, but will also be the starting point to further develop and eventually position our platform products along the entire spectrum of the medical value chain, from the inception of novel therapies to their application at the point-of-care.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been human-validated.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been human-validated.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC-ACC - HORIZON EIC Accelerator
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2025-ACCELERATOR-02
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80469 MUNCHEN
Germany
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.