Objective Drug discovery is data-hungry and all major pharmaceutical companies maintain extensive in-house instances of public data alongside internal. Analysis and hypothesis generation for drug-discovery projects requires assembly, overlay and comparison of data from many sources, requiring shared identifiers and common semantics. Expression profiles need to be overlaid with gene or pathway identifiers and reports on compound pharmacology. Alignment and integration of internal and public data and information sources is a significant effort and the process is repeated across companies, institutes and academic laboratories. This represents a significant waste and an opportunity cost. To address these challenges, the Open PHACTS project will develop an open access innovation platform, Open Pharmacological Space (OPS), via a semantic web approach. OPS will comprise data, vocabularies and infrastructure needed to accelerate drug-oriented research. This semantic integration hub will remove key bottlenecks in small molecule drug discovery: disparate information sources, lack of standards and common identifiers, guided by well defined research questions from drug discovery. Workflows for data capture, processing, interoperability, visualization, and chemogenomics will be developed creating a comprehensive Systems Chemical Biology Analysis Network. Security issues around proprietary data, shared via the Open PHACTS Discovery Platform and accessible for safe querying and reasoning will be properly addressed with expert trusted parties.The Open PHACTS consortium comprises 20 European academic and SME partners, with leading experts in the fields of data mining, annotation, small molecule data storage and manipulation, target bioinformatics, RDF information handling, massive in silico reasoning and chemical biology. The 10 EFPIA members of Open PHACTS will contribute drug discovery expertise, data sets, software engineering and programming capacity to the project. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencescomputer and information sciencessoftwarenatural sciencescomputer and information sciencesdata sciencedata miningnatural sciencescomputer and information sciencesinternetsemantic web Programme(s) FP7-JTI - Specific Programme "Cooperation": Joint Technology Initiatives Topic(s) IMI-JU-02-2009-08 - Knowledge Management – Open Pharmacological Space Call for proposal IMI-JU-02-2009 See other projects for this call Funding Scheme JTI-CP-IMI - Joint Technology Initiatives - Collaborative Project (IMI) Coordinator GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD. Address Great west road 980 TW89GS Brentford United Kingdom See on map Region London Outer London — West and North West Hounslow and Richmond upon Thames Principal investigator Stefan Senger (Dr) Administrative Contact Karen Louise Philpott (Dr) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 0,00 Participants (30) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAT WIEN Austria EU contribution € 1 640 800,00 Address Universitatsring 1 1010 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Administrative Contact Anika Robl (MA) Links Contact the organisation Opens in new window Website Opens in new window DANMARKS TEKNISKE UNIVERSITET Denmark EU contribution € 649 038,00 Address Anker engelunds vej 101 2800 Kongens lyngby See on map Region Danmark Hovedstaden Københavns omegn Activity type Higher or Secondary Education Establishments Administrative Contact Arturas Maslauskas (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAET HAMBURG Germany EU contribution € 483 011,00 Address Mittelweg 177 20148 Hamburg See on map Region Hamburg Hamburg Hamburg Activity type Higher or Secondary Education Establishments Administrative Contact Martin Pagel de Souza (Mr.) Links Contact the organisation Opens in new window Website Opens in new window BIOSOLVEIT GMBH Germany EU contribution € 576 364,00 Address An der ziegelei 79 53757 Sankt augustin See on map Region Nordrhein-Westfalen Köln Rhein-Sieg-Kreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Gloria Kraschinski (Ms.) Links Contact the organisation Opens in new window Website Opens in new window CONSORCIO MAR PARC DE SALUT DE BARCELONA Spain EU contribution € 724 540,00 Address Paseo maritim 25-29 08003 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Administrative Contact Andreu Fort (Mr) Links Contact the organisation Opens in new window Website Opens in new window ACADEMISCH ZIEKENHUIS LEIDEN Netherlands EU contribution € 611 304,00 Address Albinusdreef 2 2333 ZA Leiden See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Administrative Contact Rudi Esveld (bc.) Links Contact the organisation Opens in new window Website Opens in new window THE ROYAL SOCIETY OF CHEMISTRY United Kingdom EU contribution € 985 540,00 Address Milton road - thomas graham house - science park CB4 0WF Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Other Administrative Contact Richard KIDD (Mr) Links Contact the organisation Opens in new window Website Opens in new window STICHTING VU Netherlands EU contribution € 760 630,00 Address De boelelaan 1105 1081 HV Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Administrative Contact Dirkje Schinkelshoek (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III Spain EU contribution € 390 200,00 Address C melchor fernandez almagro 3 28029 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Administrative Contact Juan Arroyo (Mr) Links Contact the organisation Opens in new window Website Opens in new window THE UNIVERSITY OF MANCHESTER United Kingdom EU contribution € 911 144,00 Address Oxford road M13 9PL Manchester See on map Region North West (England) Greater Manchester Manchester Activity type Higher or Secondary Education Establishments Administrative Contact Phillip McDonald (Mr) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITEIT MAASTRICHT Netherlands EU contribution € 560 308,00 Address Minderbroedersberg 4 6200 MD Maastricht See on map Region Zuid-Nederland Limburg (NL) Zuid-Limburg Activity type Higher or Secondary Education Establishments Administrative Contact Pascal Stevens (MSc RC) Links Contact the organisation Opens in new window Website Opens in new window Academic Concept Knowledge Limited Participation ended United Kingdom EU contribution € 359 019,00 Address Norman avenue KT17 3AB Epsom See on map Administrative Contact John A Michael (Commercial Director) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSIDAD DE SANTIAGO DE COMPOSTELA Spain EU contribution € 357 520,00 Address Colexio de san xerome praza do obradoiro s/n 15782 Santiago de compostela See on map Region Noroeste Galicia A Coruña Activity type Higher or Secondary Education Establishments Administrative Contact Fernando Sedano Arnaez (Dr.) Links Contact the organisation Opens in new window Website Opens in new window RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN Germany EU contribution € 414 263,00 Address Regina pacis weg 3 53113 Bonn See on map Region Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Gertrud Frankenreiter (Ms.) Links Contact the organisation Opens in new window Website Opens in new window ASTRAZENECA AB Sweden EU contribution € 0,00 Address Vastra maelarhamnen 151 85 Sodertaelje See on map Region Östra Sverige Stockholm Stockholms län Administrative Contact Eva Lindgren (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window PFIZER LIMITED United Kingdom EU contribution € 0,00 Address Ramsgate road CT13 9NJ Sandwich See on map Region South East (England) Kent East Kent Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Olga Krylova (Dr) Links Contact the organisation Opens in new window Website Opens in new window ESTEVE PHARMACEUTICALS, SA Spain EU contribution € 0,00 Address Passeig de la zona franca 109, 4a planta 08038 Barcelona See on map Region Este Cataluña Barcelona Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Eduard Valenti (Dr) Links Contact the organisation Opens in new window Website Opens in new window NOVARTIS PHARMA AG Switzerland EU contribution € 0,00 Address Lichtstrasse 35 4056 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Barbara Stolz (PhD) Links Contact the organisation Opens in new window Website Opens in new window MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN Germany EU contribution € 0,00 Address Frankfurter strasse 250 64293 Darmstadt See on map Region Hessen Darmstadt Darmstadt, Kreisfreie Stadt Administrative Contact Ninog Péresse (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window H. LUNDBECK AS Denmark EU contribution € 0,00 Address Ottiliavej 7-9 2500 Valby See on map Region Danmark Hovedstaden Byen København Administrative Contact Ejner Knud Moltzen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window ELI LILLY AND COMPANY LTD United Kingdom EU contribution € 0,00 Address Lilly house basingview RG21 4FA Basingstoke See on map Region South East (England) Hampshire and Isle of Wight North Hampshire Administrative Contact Birgit Steckel-Hamann (Dr) Links Contact the organisation Opens in new window Website Opens in new window STICHTING DTL PROJECTS Netherlands EU contribution € 280 350,00 Address Jaarbeursplein 6, 6th floor beatrixgebouw jaarbeurs 3521 AL Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Research Organisations Administrative Contact Leonie Hek (Miss) Links Contact the organisation Opens in new window Website Opens in new window SIB SWISS INSTITUTE OF BIOINFORMATICS Switzerland EU contribution € 568 776,00 Address Rue michel servet 1 cmu 1206 Geneve See on map Region Schweiz/Suisse/Svizzera Région lémanique Genève Activity type Research Organisations Administrative Contact Jocelyne BOCQUET (Head of finances) Links Contact the organisation Opens in new window Website Opens in new window Connected Discovery Ltd United Kingdom EU contribution € 386 238,00 Address The strand CT147DP Walmer, deal See on map Administrative Contact Bryn Williams-Jones (Mr) Links Contact the organisation Opens in new window Website Opens in new window EUROPEAN MOLECULAR BIOLOGY LABORATORY Germany EU contribution € 183 340,00 Address Meyerhofstrasse 1 69117 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Administrative Contact Agnieszka Egan (Mrs) Links Contact the organisation Opens in new window Website Opens in new window JANSSEN PHARMACEUTICA NV Belgium EU contribution € 0,00 Address Turnhoutseweg 30 2340 Beerse See on map Region Vlaams Gewest Prov. 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Turnhout Administrative Contact Koen Meeussen (Dr.) Links Contact the organisation Opens in new window Website Opens in new window OPENLINK GROUP LIMITED United Kingdom EU contribution € 413 890,00 Address Purley way airport house 137 CR0 0XZ Croydon See on map Region London Outer London — South Croydon Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Hugh Williams (Mr) Links Contact the organisation Opens in new window Website Opens in new window OPEN PHACTS FOUNDATION LBG United Kingdom EU contribution € 121 195,00 Address Milton road 290 292 science park thomas graham house CB4 0WF Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Research Organisations Administrative Contact Richard Kidd (Mr) Links Contact the organisation Opens in new window Website Opens in new window ALMIRALL SA Spain EU contribution € 0,00 Address General mitre 151 08022 Barcelona See on map Region Este Cataluña Barcelona Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact JORGE BELETA SUPERVIA (Dr.) Links Contact the organisation Opens in new window Website Opens in new window SciBite Limited United Kingdom EU contribution € 88 963,00 Address Office 8 TN40 1QF Bexhill-on-sea See on map Administrative Contact Lee Harland (Director) Links Contact the organisation Opens in new window Website Opens in new window
