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Models Of Patient Engagement for Alzheimer’s Disease - Sofia ref.: 115985

Objective

The MOPEAD consortium has proposed a programme of work carefully aligned to the objectives of IMI2 Call to deliver a step-change in AD-related patient engagement (PE) strategies and a paradigm shift in early stage care. It aims to improve patient engagement in three categories: 1) Pre-clinical AD (the most important for prevention trials; 2) Prodromal AD (i.e. MCI with positive amyloid biomarkers); and 3) Very Mild AD. MOPEAD offers four different and complementary strategies, namely AD Citizen-Science, Open House Initiative (OHI), Primary Care Campaign (PCC), and Type 2 Diabetes (T2DM). It seeks subjects eligible for CT scan in all three mentioned categories. The central concept is to test and evaluate the four Patient Engagement models (Runs) to help identify patients at risk of AD in a five-country, multi-centre setting. It builds upon an already successful model, the Open House Initiative pioneered by the coordinator (FACE). Five countries (ES, DE, NL, SE and SL) have been selected to implement these models based upon relevant expertise; the consortium brings together partners for their potential to become long-term assets to European efforts to tackle AD challenges. The methodology involves enhanced pre-screening protocols to select individuals for conventional screening associated to an RCT. Eligible subjects will be invited to formal evaluation using a protocol consensus with EPFIA. MOPEAD possesses confident baseline metrics from which to measure progress and determine the efficacy of PE strategies compared to primary care. Although baseline data exists for only three of the four proposed models, the new model AD Citizen Science approach will add significantly to the holistic approach of the project. The proposal addresses the specific cross-border challenge of improving health care and reducing the economic burden related to AD by means of identifying those patients at risk of developing AD. This will cover a significant gap in the healthcare system.

Call for proposal

H2020-JTI-IMI2-2015-05-two-stage
See other projects for this call

Coordinator

FUNDACIO ACE
Address
Marques De Sentmenat 57
08014 Barcelona
Spain
Activity type
Research Organisations
EU contribution
€ 311 684,93

Participants (14)

ELI LILLY AND COMPANY LTD
United Kingdom
EU contribution
€ 0
Address
Lilly House Basingview
RG21 4FA Basingstoke
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASDM CONSULTING
Belgium
EU contribution
€ 118 299,31
Address
Rue De La Vignette 96 Boite 9
1160 Auderghem
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASTRAZENECA AB
Sweden
EU contribution
€ 0
Address
Vastra Maelarhamnen
151 85 Sodertaelje
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EUROPEAN INSTITUTE OF WOMEN'S HEALTH COMPANY LIMITED BY GUARANTEE
Ireland
EU contribution
€ 45 688
Address
Pearse Street 33
2 Dublin
Activity type
Research Organisations
GMV SOLUCIONES GLOBALES INTERNET SAU
Spain
EU contribution
€ 380 593,75
Address
Calle Isaac Newton 11 Parque Tecnologico De Madrid
28760 Tres Cantos Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 468 701,73
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
KITE INNOVATION (EUROPE) LIMITED

Participation ended

United Kingdom
EU contribution
€ 34 538,49
Address
3M Buckley Innovation Centre
HD1 3BD Huddersfield
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SPOMINCICA ALZHEIMER SLOVENIJA SLOVENSKO ZDRUZENJE ZA POMOC PRI DEMENCI
Slovenia
EU contribution
€ 25 991,43
Address
Luize Pesjakove 9
1000 Ljubljana
Activity type
Other
KLINIKUM DER UNIVERSITAET ZU KOELN
Germany
EU contribution
€ 144 106,90
Address
Kerpener Strasse 62
50937 Koeln
Activity type
Higher or Secondary Education Establishments
UNIVERZITETNI KLINICNI CENTER LJUBLJANA
Slovenia
EU contribution
€ 168 306,79
Address
Zaloska Cesta 002
1000 Ljubljana
Activity type
Higher or Secondary Education Establishments
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
Spain
EU contribution
€ 74 322,40
Address
Passeig Vall D Hebron 119-129 Edificio De Recerca
08035 Barcelona
Activity type
Research Organisations
STICHTING VUMC
Netherlands
EU contribution
€ 97 347,69
Address
De Boelelaan 1117
1081 HV Amsterdam
Activity type
Research Organisations
ALZHEIMER EUROPE
Luxembourg
EU contribution
€ 91 275
Address
Rue Dicks 14
1417 Luxembourg
Activity type
Other
MODUS RESEARCH AND INNOVATION LIMITED
United Kingdom
EU contribution
€ 82 143,58
Address
7-11 Melville Street
EH3 7PE Edinburgh
Activity type
Research Organisations