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Models Of Patient Engagement for Alzheimer’s Disease - Sofia ref.: 115985

Objective

The MOPEAD consortium has proposed a programme of work carefully aligned to the objectives of IMI2 Call to deliver a step-change in AD-related patient engagement (PE) strategies and a paradigm shift in early stage care. It aims to improve patient engagement in three categories: 1) Pre-clinical AD (the most important for prevention trials; 2) Prodromal AD (i.e. MCI with positive amyloid biomarkers); and 3) Very Mild AD. MOPEAD offers four different and complementary strategies, namely AD Citizen-Science, Open House Initiative (OHI), Primary Care Campaign (PCC), and Type 2 Diabetes (T2DM). It seeks subjects eligible for CT scan in all three mentioned categories. The central concept is to test and evaluate the four Patient Engagement models (Runs) to help identify patients at risk of AD in a five-country, multi-centre setting. It builds upon an already successful model, the Open House Initiative pioneered by the coordinator (FACE). Five countries (ES, DE, NL, SE and SL) have been selected to implement these models based upon relevant expertise; the consortium brings together partners for their potential to become long-term assets to European efforts to tackle AD challenges. The methodology involves enhanced pre-screening protocols to select individuals for conventional screening associated to an RCT. Eligible subjects will be invited to formal evaluation using a protocol consensus with EPFIA. MOPEAD possesses confident baseline metrics from which to measure progress and determine the efficacy of PE strategies compared to primary care. Although baseline data exists for only three of the four proposed models, the new model AD Citizen Science approach will add significantly to the holistic approach of the project. The proposal addresses the specific cross-border challenge of improving health care and reducing the economic burden related to AD by means of identifying those patients at risk of developing AD. This will cover a significant gap in the healthcare system.

Coordinator

FUNDACIO ACE
Net EU contribution
€ 311 684,93
Address
Marques De Sentmenat 57
08014 Barcelona
Spain

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 567 268,98

Participants (15)

ELI LILLY AND COMPANY LTD
United Kingdom
Net EU contribution
€ 0,00
Address
Lilly House Basingview
RG21 4FA Basingstoke

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Region
South East (England) Hampshire and Isle of Wight North Hampshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 1 000 000,00
ASDM CONSULTING
Belgium
Net EU contribution
€ 118 299,31
Address
Rue De La Vignette 96 Boite 9
1160 Auderghem

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 12 874,44
ASTRAZENECA AB
Sweden
Net EU contribution
€ 0,00
Address
Vastra Maelarhamnen
151 85 Sodertaelje

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 67 251,00
EUROPEAN INSTITUTE OF WOMEN'S HEALTH COMPANY LIMITED BY GUARANTEE
Ireland
Net EU contribution
€ 45 688,00
Address
Pearse Street 33
2 Dublin

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Region
Ireland Northern and Western Border
Activity type
Research Organisations
Non-EU contribution
€ 2 925,00
GMV SOLUCIONES GLOBALES INTERNET SAU
Spain
Net EU contribution
€ 380 593,75
Address
Calle Isaac Newton 11 Parque Tecnologico De Madrid
28760 Tres Cantos Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 91 872,50
KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 428 441,73
Address
Nobels Vag 5
17177 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 85 268,27
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

REGION STOCKHOLM
Sweden
Net EU contribution
€ 40 260,00
Address
Hantverkargatan 45
104 22 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
KITE INNOVATION (EUROPE) LIMITED

Participation ended

United Kingdom
Net EU contribution
€ 34 538,49
Address
3m Buckley Innovation Centre
HD1 3BD Huddersfield

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Yorkshire and the Humber West Yorkshire Calderdale and Kirklees
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
SPOMINCICA ALZHEIMER SLOVENIJA SLOVENSKO ZDRUZENJE ZA POMOC PRI DEMENCI
Slovenia
Net EU contribution
€ 25 991,43
Address
Luize Pesjakove 9
1000 Ljubljana

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Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Other
Non-EU contribution
€ 2 058,75
KLINIKUM DER UNIVERSITAET ZU KOELN
Germany
Net EU contribution
€ 144 106,90
Address
Kerpener Strasse 62
50937 Koeln

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Region
Nordrhein-Westfalen Köln Köln, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 239 638,44
UNIVERZITETNI KLINICNI CENTER LJUBLJANA
Slovenia
Net EU contribution
€ 168 306,79
Address
Zaloska Cesta 002
1000 Ljubljana

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Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 61 092,12
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
Spain
Net EU contribution
€ 74 322,40
Address
Passeig Vall D Hebron 119-129 Edificio De Recerca
08035 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
STICHTING VUMC
Netherlands
Net EU contribution
€ 97 347,69
Address
De Boelelaan 1117
1081 HV Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Research Organisations
Non-EU contribution
€ 396 218,75
ALZHEIMER EUROPE
Luxembourg
Net EU contribution
€ 91 275,00
Address
Rue Dicks 14
1417 Luxembourg

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Luxembourg Luxembourg Luxembourg
Activity type
Other
Non-EU contribution
€ 6 250,00
MODUS RESEARCH AND INNOVATION LIMITED
United Kingdom
Net EU contribution
€ 82 143,58
Address
7-11 Melville Street
EH3 7PE Edinburgh

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Eastern Scotland Edinburgh
Activity type
Research Organisations
Non-EU contribution
€ 6 249,55