Biomaterials and drug delivery systems are complex composite systems, often made by applying organic solvents and additives, which have well-known disadvantages like toxicity and flammability. Furthermore, with increasing materials complexity and size red uction to nanoscale, classical solvent approaches are destructive because the used liquids destroy the functional surfaces they are helping to create, due to viscosity and surface tension. Technology based on supercritical carbon dioxide (SCCO2) is an a lternative to overcome the problems associated with the use of traditional solvents. SCCO2 is a non-destructive solvent adequate to manipulate complex functional materials and nanostructures. Furthermore, the technology allows obtaining end-products free of residual solvents. SCCO2 technology is proposed here for the production of a great range of knowledge-based multifunctional materials with better control of surface properties and purity, and for the industrial - high-rate, high-volume - fabrication of surface hybridized or composite materials. The project is centered in pharmaceuticals (drug delivery and targeting with biomacromolecules), biomedical (tissue engineering) and cosmetics (ointmers) products prepared using this technology. Moreover, tech nology transfer to the plastics and fillers industries is addressed.
Fields of science
- FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006.
Call for proposal
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Funding SchemeSTREP - Specific Targeted Research Project