Objective
NANOSPAD aims to develop a highly sensitive system for rapid analysis of protein micro-arrays, with compact size and features suitable for use by general practitioners. It will represent a demonstration of a methodology suitable in general to the rapidly growing field of proteomics and will be validated in allergy diagnostics (serum allergen-specific IgE). NANOSPAD is focused on miniaturization as an effective way of achieving improved performance for analytical methods. It will therefore pursue new developments in diversified technologies: optoelectronics, microelectronics, micro-fluidics, surface chemistry, chemiluminescence and electro-chemiluminescence.
A new monolithic matrix detector of Single-Photon Avalanche Diodes (SPAD) will be developed in silicon microelectronic technology, with each element capable of detecting single optical photons with high quantum efficiency and low noise and number of elements matched to the number of spots in a microarray. This detector will be the base for the design and fabrication of a prototype of compact analytical apparatus, where the detector elements must be conjugated to the spots of the microarray and various electronic, optical, mechanical and microfluidic subsystems must efficiently interact. New coating techniques will be established for the surface of the microarray substrates (glass, silicon, ITO) with polymers for specific bonding of target proteins.
Chemiluminescent and electro-luminescent labels will be developed, aiming to enable highly sensitive measurement of serum IgE and avoid problems associated with laser excitation of fluorescent probes. Dedicated software will be developed for making possible easy and efficient operation of the apparatus by general practitioners and for a better understanding, evaluation and dissemination of the data obtained by exploiting ICT facilities. NANOSPAD will create and maintain a website, will carry out a market study and will elaborate an exploitation plan.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences classical mechanics fluid mechanics microfluidics
- natural sciences physical sciences electromagnetism and electronics optoelectronics
- engineering and technology materials engineering coating and films
- engineering and technology materials engineering amorphous solids
- natural sciences chemical sciences inorganic chemistry metalloids
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
20133 MILANO
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.