Objective
Multifunctional dendrimers have emerged as potential candidates for targeted drug delivery systems. In the proposed project, dendrons with different surface groups will be synthesized via convergent methodology. New synthetic methods will be developed to obtain dendrimers from combination of such dendrons.
Dendrimers having targeting groups and drug moieties conjugated at the surface will be synthesized with the aim of targeted drug delivery to colon and bone. Recently, colon targeting became much more attractive for delivery of drug molecules due to the low digestive enzymatic activity and high residence time compared to the stomach and small intestine. Also, for treatments of local diseases of the colon like ulcerative colitis, Crohn's disease and colon cancer, drug targeting not only reduces the dose to be administered, but also reduces the incidence of possible adverse effects associated with these chemotherapeutic agents. Along with colon targeting, segmented dendrons having bisphosphonate groups, as bone-targeting agents will be synthesized. These multi-functional dendrimers will then be evaluated for their efficiency towards bone adenocarcinoma.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology prostate cancer
- medical and health sciences clinical medicine gastroenterology inflammatory bowel disease
- medical and health sciences clinical medicine oncology colorectal cancer
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-12
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IRG - Marie Curie actions-International re-integration grants
Coordinator
ISTANBUL
Türkiye
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.