Objective The objective of the proposed project is to develop new medical diagnostic tools based on the most sensitive detector technologies available today. A common denominator for the technologies is reading out the biological state in the magnetic domain. This will be accomplished by using both magnetic nanoparticles as substrates or tags for biological reactions and reading out the atomic nuclear spin. The latter technology is a development from the inductive readout in Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI). The technology used in this project is a pure magnetic field read-out system, which quite contrary to the inductive method has a sensitivity which is more or less independent of frequency and magnetic field down to very low fields. The several competing technologies will be benchmarked against each other with a model system consisting of biotin and streptavidine in order to gain a unique understanding of the differences and advantages with the different systems. To validate the concept(s), real diagnostic test will be done on in vitro detection of F1 antigen (y. pestis) Mycobacterium tuberculosis in urine samples and detection of Yersinia pestis F1 antigen in environmental samples (bio terrorism). Further to the validation, neuroimaging and instrumentation for diagnosis of neurological diseases will be investigated in vivo. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesbiological sciencesbiophysicsengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imagingengineering and technologynanotechnologynano-materialsnatural sciencesphysical scienceselectromagnetism and electronicssuperconductivity Keywords Nanotechnology Programme(s) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Topic(s) NMP-2004-IST-NMP-2 - Bio-sensors for Diagnosis and Healthcare Call for proposal FP6-2004-IST-NMP-2 See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator CHALMERS TEKNISKA HOEGSKOLA AB Address Chalmersplatsen 4 Goeteborg Sweden See on map Links Website Opens in new window EU contribution € 0,00 Participants (12) Sort alphabetically Sort by EU Contribution Expand all Collapse all IMEGO AB Sweden EU contribution € 0,00 Address Arvid hedvalls backe 4 Goeteborg See on map Links Website Opens in new window KAROLINSKA INSTITUTET Sweden EU contribution € 0,00 Address Nobels vaeg 5 Stockholm See on map Links Website Opens in new window KUNGLIGA TEKNISKA HÖGSKOLAN Sweden EU contribution € 0,00 Address Valhallavägen 79 Stockholm See on map Links Website Opens in new window FORSCHUNGSZENTRUM JUELICH GMBH Germany EU contribution € 0,00 Address Leo-brandt-strasse Juelich See on map Links Website Opens in new window JUELICHER SQUID GMBH Germany EU contribution € 0,00 Address Lankenstrasse 29 Juelich See on map Links Website Opens in new window PHYSIKALISCH-TECHNISCHE BUNDESANSTALT Germany EU contribution € 0,00 Address Bundesallee 100 Braunschweig See on map Links Website Opens in new window CHEMICELL GMBH Germany EU contribution € 0,00 Address Wartburgstrasse 6 Berlin See on map Links Website Opens in new window FRIEDRICH-SCHILLER-UNIVERSITAET JENA. Germany EU contribution € 0,00 Address Fuerstengraben 1 Jena See on map Links Website Opens in new window MICRO-SPHERE S.A. Switzerland EU contribution € 0,00 Address Via cantonale Madonna del piano See on map ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE. United Kingdom EU contribution € 0,00 Address Egham hill Egham, surrey See on map Links Website Opens in new window DANMARKS TEKNISKE UNIVERSITET Denmark EU contribution € 0,00 Address Anker engelundsvej 1, bygning 101a Kongens lyngby See on map Links Website Opens in new window SENOVA GESELLSCHAFT FÜR BIOWISSENSCHAFT UND TECHNIK MBH Germany EU contribution € 0,00 Address Winzerlaerstr.2 Jena See on map Links Website Opens in new window