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Content archived on 2024-06-16

Integrating enzymes, mediators and nanostructures to provide bio-powered bio-electrochemical sensing systems

Objective

BIO-MEDNANO STREP-project focuses on research at the frontiers of knowledge of enzymes, mediators, surfaces and immobilisation strategies aimed at improving enzymatic electron transfer reactions for application towards integrated bio-powered biosensing systems for diagnosis and healthcare. Such improvements will be provided by: screening for novel enzymes; modification of enzymes; design of novel nano-structured scaffolds for enzyme immobilization, to provide devices with improved stability and electron transfer efficiency (sensitivity and/or power output).

The main scientific objective of the BIO-MEDNANO STREP -project is to increase understanding and overcome the present limitations of biofuel cell and biosensor devices based on biological electron transfer systems. The technological aim of the project, integrated bio-powered biosensing systems, will be achieved by using multidisciplinary approaches exploiting knowledge in modern biotechnology, electrochemistry, and surface and material science. Optimisation of electron transfer between the enzyme molecule and the electrode will be the challenging focus of this research, due to its generic applicability and importance. The long-term innovation of the project is to generate profound, molecular level knowledge on the electron transfer process taking place between biological molecules and electrochemically active materials and further apply this knowledge to integrated bio-powered biosensing systems. The initial targets for integrated biosensing systems will be based on development of prototype biosensors for the intermittent determination of glucose and catecholamine neurotransmitter levels in clinical samples, powered by a biofuel cell functioning on in-vivo available biofuels. The ambitious long-term aim of the development of such prototypes is to provide integrated bio-powered autonomous implantable biosensing systems for healthcare monitoring.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-IST-NMP-2
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

NATIONAL UNIVERSITY OF IRELAND, GALWAY
EU contribution
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (6)

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