Objective
Our objective is to create the conditions for the rapid progress of research on the molecular principles of post-translational modifications of proteins by linkage of ubiquitin and ubiquitin-like molecules, the regulatory role of such modifications in basi c biological processes and their implications for pathological conditions that represent urgent socio-economic and human needs such as chronic inflammation, neurodegeneration and cancer. The RUBICON consortium will take a multi-disciplinary and multifacet ed approach to these problems. To enhance interdisciplinary research, RUBICON brings together investigators from different backgrounds that will work at all levels of a drug discovery oriented process. The organisation of the Joint Programme infrastructure s include shared RUBICON-funded core facilities and a web database serving as a European repository for biological research tools. Training will be provided by: a competitive programme of multi-centre postdoctoral fellowships, by mobility of scientists to RUBICON centres and platforms, and by open-lab meetings, summer schools and workshops. To feed back the benefits of integration into EU society, we have identified associated research groups and will open network meetings and fellowship programs to young investigators and scientists from new European countries. We aim to integrate research efforts within the first 18 months of the project, and then build on the infrastructure and collaborations established in order to enhance the competitiveness of Europea n research on ubiquitin and ubiquitin-like modifications, and promote, in concert with SMEs, the emergence of novel mechanism-based therapeutic approaches to diseases associated with disturbance of these basic regulatory processes.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- natural sciences computer and information sciences databases
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-LIFESCIHEALTH-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
STOCKHOLM
Sweden
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Participants (22)
AMSTERDAM
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85500 UTRECHT
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LONDON
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DUNDEE
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PARIS
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STRASBOURG
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MARTINSRIED
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GOETTINGEN
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BERLIN
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MILAN
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HAIFA
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JERUSALEM
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2098 LELYSTAD
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ABCOUDE
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REHOVOT
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2098 LELYSTAD
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EXETER
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HEIDELBERG
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ORSAY
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KONSTANZ
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STUTTGART
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KÖLN
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