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Content archived on 2024-05-29

Development and preclinical testing of cord blood-derived cell therapy products

Objective

Cord blood is a widely recognized source of hematopoietic progenitor cells for human transplantation in pediatric and, to a lesser extent, also adult patients affected by different hematological disorders. The therapeutic perspectives of cord blood has been recently widened by the discovery that it contains pluripotent stem cells, capable to give rise, in vitro and in vivo, to other than hematopoietic cells. The present project is aimed at investigating the potential of cord blood stem cells for differentiation and tissue repair, with the final goal to develop novel technologies for pre-clinical testing of cord blood-derived cell therapy products.

Therefore, the main part of this project will be dedicated to set up and validate innovative technologies for the isolation, amplification and differentiation of pluripotent cells from cord blood, including immunological assays for the evaluation of their immunoreactivity and animal models of human diseases to test their safety and efficacy. Moreover, the presence of a SME in the Consortium is specifically aimed at translate the results obtained from the basic science into GMP procedures to be used in phase I/II clinical protocols.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-LIFESCIHEALTH-5
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
EU contribution
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (7)

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