Objective
The EUCOMM integrated project responds to the priority topic defined by Priority 1. Life Sciences and Biotechnology for Health, 'Genome-wide Mutagenesis in Mouse'. EUCOMM integrates European skills, efforts, resources, and infrastructure to produce, in a systematic high throughput way, mutations throughout the mouse genome. A collection of up to 20.000 mutated genes will be generated in mouse embryonic stem (ES) cells using conditional gene trapping and gene targeting approaches. This library will enable mouse mutants to be established worldwide in a standardized and cost-effective manner, making mouse mutants available to a much wider biomedical research community than has been possible previously. For a subset of genes relevant for human disease, mutant mice will be established, archived and analyzed. This will offer an opportunity to decipher molecular disease mechanisms and in some cases provide a foundation for the development of diagnostic, prognostic and therapeutic strategies. This project is built on exceptionally strong European expertise in mouse molecular genetics, genomics and bioinformatics and will enable automation of targeting vector production and professional dissemination of material. EUCOMM will foster integration with existing European consortia which address mouse gene expression analysis, mutant phenotyping, imaging and archiving. Progress of all of these projects will be enhanced by EUCOMM mouse mutants. All targeting vectors, mutant ES cells, mouse resources, and Standard Operating Procedures generated by EUCOMM will be displayed to the scientific community via the EUCOMM web linked database, other EU consortia databases and the Ensembl browser, and distributed professionally. Taken together, EUCOMM will make a major contribution to the analysis of gene function. Finally, EUCOMM resources represent major opportunities for exploitation by SMEs and the pharmaceutical industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences molecular biology molecular genetics
- natural sciences computer and information sciences databases
- social sciences sociology industrial relations automation
- natural sciences biological sciences genetics RNA transcriptomes
- natural sciences biological sciences genetics genomes
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-LIFESCIHEALTH-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NEUHERBERG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.